The Role of the Autonomic Nerves System in the Etiology and Pathogenesis of Essential Hypertension
The analysis of autonomic functions in the normal regulation of blood pressure and in patients suffering from essential hypertension results in the hypothesis that hyperactivity of the hypothalamic sympathetic center plays a major role in the etiology and pathogenesis of essential hypertension. Pres...
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Veröffentlicht in: | JAPANESE CIRCULATION JOURNAL 1970/05/20, Vol.34(3), pp.147-153 |
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description | The analysis of autonomic functions in the normal regulation of blood pressure and in patients suffering from essential hypertension results in the hypothesis that hyperactivity of the hypothalamic sympathetic center plays a major role in the etiology and pathogenesis of essential hypertension. Presumably there are hereditary factors leading to hyperactivity of the sympathetic center. In addition environmental factors are essential for an increased activity of the pressor center and for the manifestation of essential hypertension. Simultaneously hormonal mechanisms may be activated by summation effects. Regarding essential hypertension as a result of sympathetic hyperactivity, modern treatment of hypertension can no longer be considered as a symptomatic but causal therapy. Hypertensive regulatory dysfunctions constitute a suitable model for studying sympathetic hyperactivity. |
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subjects | Animals Autonomic Nervous System - physiopathology Blood Pressure Cats Cerebral Cortex - physiopathology Female Humans Hypertension - etiology Hypertension - physiopathology Hypertension - therapy Hypothalamus - physiopathology Limbic System - physiopathology Male Models, Biological Muscles Pulse Respiration Sex Factors Stress, Physiological |
title | The Role of the Autonomic Nerves System in the Etiology and Pathogenesis of Essential Hypertension |
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