The effect of refeeding on pancreatic exocrine function in marasmic infants
Volume, pH, bicarbonate, amylase, and lipase of duodenal contents were measured under baseline conditions and after stimulation with pancreozymin in marasmie children both before and after 30 days of intensive rehabilitation. There were no differences in secretory rate, pH, or bicarbonate output fro...
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Veröffentlicht in: | The Journal of pediatrics 1970-08, Vol.77 (2), p.334-337 |
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container_title | The Journal of pediatrics |
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creator | Osvaldo Danus, V. Ana Maria Urbina, Q.F. Valenzuela, Ida Giorgio Solimano, C. |
description | Volume, pH, bicarbonate, amylase, and lipase of duodenal contents were measured under baseline conditions and after stimulation with pancreozymin in marasmie children both before and after 30 days of intensive rehabilitation. There were no differences in secretory rate, pH, or bicarbonate output from those of control values. Base-line enzymatic activity, especially lipase activity, was markedly reduced in marasmic children both before and after therapy, as was the response to pancreozymin. Thus exocrine function of the pancreas is affected during marasmus, and recovery does not occur even after 30 days of intensive therapy. |
doi_str_mv | 10.1016/S0022-3476(70)80347-X |
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There were no differences in secretory rate, pH, or bicarbonate output from those of control values. Base-line enzymatic activity, especially lipase activity, was markedly reduced in marasmic children both before and after therapy, as was the response to pancreozymin. Thus exocrine function of the pancreas is affected during marasmus, and recovery does not occur even after 30 days of intensive therapy.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/S0022-3476(70)80347-X</identifier><identifier>PMID: 5431213</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Amylases - metabolism ; Bicarbonates - metabolism ; Cholecystokinin - metabolism ; Cholecystokinin - pharmacology ; Diet Therapy ; Humans ; Infant ; Infant Nutrition Disorders - enzymology ; Infant Nutrition Disorders - physiopathology ; Infant Nutrition Disorders - therapy ; Lipase - metabolism ; Pancreas - enzymology ; Pancreas - physiopathology ; Pancreatic Juice - analysis</subject><ispartof>The Journal of pediatrics, 1970-08, Vol.77 (2), p.334-337</ispartof><rights>1970 The C. V. 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There were no differences in secretory rate, pH, or bicarbonate output from those of control values. Base-line enzymatic activity, especially lipase activity, was markedly reduced in marasmic children both before and after therapy, as was the response to pancreozymin. Thus exocrine function of the pancreas is affected during marasmus, and recovery does not occur even after 30 days of intensive therapy.</description><subject>Amylases - metabolism</subject><subject>Bicarbonates - metabolism</subject><subject>Cholecystokinin - metabolism</subject><subject>Cholecystokinin - pharmacology</subject><subject>Diet Therapy</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant Nutrition Disorders - enzymology</subject><subject>Infant Nutrition Disorders - physiopathology</subject><subject>Infant Nutrition Disorders - therapy</subject><subject>Lipase - metabolism</subject><subject>Pancreas - enzymology</subject><subject>Pancreas - physiopathology</subject><subject>Pancreatic Juice - analysis</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotVZ_QmFWoovRm8ljpiuR4gsLLqzQXchkbjTSZmoyFf33pg-6dXUvnHMf5yNkSOGKApXXrwBFkTNeyosSLitIXT47IH0KozKXFWOHpL-3HJOTGD8BYMQBeqQnOKMFZX3yPP3ADK1F02WtzQJaxMb596z12VJ7E1B3zmT405rgPGZ25U3nkuh8ttBBx0VSnbfad_GUHFk9j3i2qwPydn83HT_mk5eHp_HtJDdMQpePrOaUCm4ttbaSEnUzEpWWdS1sTbEQNRcIjApWY8WNEQWUpqbSVDU2pmnYgJxv9y5D-7XC2KmFiwbnc-2xXUVVcVkwXpXJKLZGE9oYUza1DC59_asoqDVEtYGo1oRUCWoDUc3S3HB3YFUvsNlP7agl_WarY0r57TCoaBx6k8iFBFI1rfvnwh-y8YKA</recordid><startdate>197008</startdate><enddate>197008</enddate><creator>Osvaldo Danus, V.</creator><creator>Ana Maria Urbina, Q.F.</creator><creator>Valenzuela, Ida</creator><creator>Giorgio Solimano, C.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197008</creationdate><title>The effect of refeeding on pancreatic exocrine function in marasmic infants</title><author>Osvaldo Danus, V. ; Ana Maria Urbina, Q.F. ; Valenzuela, Ida ; Giorgio Solimano, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-9fa41154ff1ff866ead958a6bb5fb1e25b45e03153be84cc5207cb16c8bedcdd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Amylases - metabolism</topic><topic>Bicarbonates - metabolism</topic><topic>Cholecystokinin - metabolism</topic><topic>Cholecystokinin - pharmacology</topic><topic>Diet Therapy</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant Nutrition Disorders - enzymology</topic><topic>Infant Nutrition Disorders - physiopathology</topic><topic>Infant Nutrition Disorders - therapy</topic><topic>Lipase - metabolism</topic><topic>Pancreas - enzymology</topic><topic>Pancreas - physiopathology</topic><topic>Pancreatic Juice - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Osvaldo Danus, V.</creatorcontrib><creatorcontrib>Ana Maria Urbina, Q.F.</creatorcontrib><creatorcontrib>Valenzuela, Ida</creatorcontrib><creatorcontrib>Giorgio Solimano, C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Osvaldo Danus, V.</au><au>Ana Maria Urbina, Q.F.</au><au>Valenzuela, Ida</au><au>Giorgio Solimano, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of refeeding on pancreatic exocrine function in marasmic infants</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>1970-08</date><risdate>1970</risdate><volume>77</volume><issue>2</issue><spage>334</spage><epage>337</epage><pages>334-337</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>Volume, pH, bicarbonate, amylase, and lipase of duodenal contents were measured under baseline conditions and after stimulation with pancreozymin in marasmie children both before and after 30 days of intensive rehabilitation. 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subjects | Amylases - metabolism Bicarbonates - metabolism Cholecystokinin - metabolism Cholecystokinin - pharmacology Diet Therapy Humans Infant Infant Nutrition Disorders - enzymology Infant Nutrition Disorders - physiopathology Infant Nutrition Disorders - therapy Lipase - metabolism Pancreas - enzymology Pancreas - physiopathology Pancreatic Juice - analysis |
title | The effect of refeeding on pancreatic exocrine function in marasmic infants |
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