Surgical excision of the canine carotid bodies and denervation of the aortic bodies
A method of obviating the carotid and aortic body chemoreceptor response has been presented consisting of excision of the carotid bodies and denervation of the aortic body or bodies. The physiological responses of these animals to high altitude acclimatization are characterized by a marked increase...
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| Veröffentlicht in: | The Journal of surgical research 1967-10, Vol.7 (10), p.457-463 |
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| container_title | The Journal of surgical research |
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| creator | Gilfillan, Rutherford S. Cuthbertson, Elizabeth M. Hansen, Julius T. Pace, Nello |
| description | A method of obviating the carotid and aortic body chemoreceptor response has been presented consisting of excision of the carotid bodies and denervation of the aortic body or bodies. The physiological responses of these animals to high altitude acclimatization are characterized by a marked increase in erythrocyte volume, a decrease in plasma volume, and a minimal increase in total blood volume. The respiratory response to anoxia is markedly decreased and the sensitivity to inspired CO
2 at high altitude is unchanged from that at sea level. |
| doi_str_mv | 10.1016/0022-4804(67)90012-1 |
| format | Article |
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2 at high altitude is unchanged from that at sea level.</description><subject>Acclimatization - physiology</subject><subject>Altitude</subject><subject>Animals</subject><subject>Blood Pressure</subject><subject>Blood Volume</subject><subject>Carotid Body - innervation</subject><subject>Carotid Body - physiology</subject><subject>Carotid Body - surgery</subject><subject>Chemoreceptor Cells - physiology</subject><subject>Denervation</subject><subject>Dogs</subject><subject>Erythrocyte Count</subject><subject>Hematocrit</subject><subject>Hypoxia - physiopathology</subject><subject>Paraganglia, Nonchromaffin - physiology</subject><subject>Plasma Volume</subject><subject>Respiration</subject><subject>Space life sciences</subject><issn>0022-4804</issn><issn>1095-8673</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1967</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAQgIMo67r6DxR6Ej1UkzRp0osgiy9Y8LB6Dmky1Ui3WZN20X9v65bFk6dhmG9eH0KnBF8RTPJrjClNmcTsIheXBcaEpmQPTQkueCpzke2j6Q45REcxfuA-L0Q2QZMccyGZmKLlsgtvzug6gS_jovNN4qukfYfE6MY1Qwi-dTYpvXUQE93YxEIDYaPbP7D2oXVmhI7RQaXrCCdjnKHX-7uX-WO6eH54mt8uUpNx0aaZLAuugZVWFIUuS94fxBm2oAW2srSFrARIWxFJCCvAUEY1z3JBGa9oBjibofPt3HXwnx3EVq1cNFDXugHfRSVZjrGgtAfZFjTBxxigUuvgVjp8K4LV4FINotQgSuVC_bpUpG87G-d35QrsrmmU19dvtnXon9w4CCoaB40B6wKYVlnv_l_wA4fLgqs</recordid><startdate>196710</startdate><enddate>196710</enddate><creator>Gilfillan, Rutherford S.</creator><creator>Cuthbertson, Elizabeth M.</creator><creator>Hansen, Julius T.</creator><creator>Pace, Nello</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196710</creationdate><title>Surgical excision of the canine carotid bodies and denervation of the aortic bodies</title><author>Gilfillan, Rutherford S. ; Cuthbertson, Elizabeth M. ; Hansen, Julius T. ; Pace, Nello</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-38b95ae4bd799abb5847540dea70d8bd98f7e8df181149ec242a5367245f23e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1967</creationdate><topic>Acclimatization - physiology</topic><topic>Altitude</topic><topic>Animals</topic><topic>Blood Pressure</topic><topic>Blood Volume</topic><topic>Carotid Body - innervation</topic><topic>Carotid Body - physiology</topic><topic>Carotid Body - surgery</topic><topic>Chemoreceptor Cells - physiology</topic><topic>Denervation</topic><topic>Dogs</topic><topic>Erythrocyte Count</topic><topic>Hematocrit</topic><topic>Hypoxia - physiopathology</topic><topic>Paraganglia, Nonchromaffin - physiology</topic><topic>Plasma Volume</topic><topic>Respiration</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gilfillan, Rutherford S.</creatorcontrib><creatorcontrib>Cuthbertson, Elizabeth M.</creatorcontrib><creatorcontrib>Hansen, Julius T.</creatorcontrib><creatorcontrib>Pace, Nello</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of surgical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gilfillan, Rutherford S.</au><au>Cuthbertson, Elizabeth M.</au><au>Hansen, Julius T.</au><au>Pace, Nello</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical excision of the canine carotid bodies and denervation of the aortic bodies</atitle><jtitle>The Journal of surgical research</jtitle><addtitle>J Surg Res</addtitle><date>1967-10</date><risdate>1967</risdate><volume>7</volume><issue>10</issue><spage>457</spage><epage>463</epage><pages>457-463</pages><issn>0022-4804</issn><eissn>1095-8673</eissn><abstract>A method of obviating the carotid and aortic body chemoreceptor response has been presented consisting of excision of the carotid bodies and denervation of the aortic body or bodies. The physiological responses of these animals to high altitude acclimatization are characterized by a marked increase in erythrocyte volume, a decrease in plasma volume, and a minimal increase in total blood volume. The respiratory response to anoxia is markedly decreased and the sensitivity to inspired CO
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| ispartof | The Journal of surgical research, 1967-10, Vol.7 (10), p.457-463 |
| issn | 0022-4804 1095-8673 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acclimatization - physiology Altitude Animals Blood Pressure Blood Volume Carotid Body - innervation Carotid Body - physiology Carotid Body - surgery Chemoreceptor Cells - physiology Denervation Dogs Erythrocyte Count Hematocrit Hypoxia - physiopathology Paraganglia, Nonchromaffin - physiology Plasma Volume Respiration Space life sciences |
| title | Surgical excision of the canine carotid bodies and denervation of the aortic bodies |
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