Inheritable Differences in the Electrophoretic Pattern of Hemoglobin Revealed in a Local Random-Bred Colony of Albino Rats

In a local colony of random-bred Albino rats, three different patterns of hemoglobin, arbitrarily denoted as patterns I, II and III, were detected by means of starch-gel electrophoresis in a discontinuous buffer system. Mating experiments showed that rats bearing pattern I and pattern III hemoglobin...

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Veröffentlicht in:Blood 1970-04, Vol.35 (4), p.447-450
Hauptverfasser: Martinovic, Jovo V., Marinkovic, Dobrivoje V., Kanazir, Dusan T., Martinovitch, Peter N.
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container_issue 4
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container_title Blood
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creator Martinovic, Jovo V.
Marinkovic, Dobrivoje V.
Kanazir, Dusan T.
Martinovitch, Peter N.
description In a local colony of random-bred Albino rats, three different patterns of hemoglobin, arbitrarily denoted as patterns I, II and III, were detected by means of starch-gel electrophoresis in a discontinuous buffer system. Mating experiments showed that rats bearing pattern I and pattern III hemoglobin bred true. Crosses of pattern I with pattern III animals yielded only pattern II animals, and when the latter were mated inter se, the resultant F2 generation showed approximately a ratio of 1:2:1 for patterns I, II and III, respectively. When F1 animals from pattern I with pattern III crosses were mated back to animals of either parental type, the resultant ratio was found to be one pattern II: one pattern I or pattern III.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Animals
Blood Protein Electrophoresis
Crosses, Genetic
Female
Gels
Hemoglobins - analysis
Male
Rats
title Inheritable Differences in the Electrophoretic Pattern of Hemoglobin Revealed in a Local Random-Bred Colony of Albino Rats
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