Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170 255 patients from 76 randomized trials

Statins represent the largest selling class of cardiovascular drug in the world. Previous randomized trials (RCTs) have demonstrated important clinical benefits with statin therapy. We combined evidence from all RCTs comparing a statin with placebo or usual care among patients with and without prior...

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Veröffentlicht in:	QJM : An International Journal of Medicine 2011-02, Vol.104 (2), p.109-124
Hauptverfasser:	MILLS, E. J, WU, P, CHONG, G, GHEMENT, I, SINGH, S, AKL, E. A, EYAWO, O, GUYATT, G, BERWANGER, O, BRIEL, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cardiovascular Diseases - mortality Cardiovascular Diseases - prevention & control Diabetes Mellitus, Type 2 - chemically induced Female General aspects Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Male Medical sciences Middle Aged Randomized Controlled Trials as Topic - methods Randomized Controlled Trials as Topic - standards Research Design Risk Factors
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