Quantitation of immunoglobulins in normal children
A modified radial immunodiffusion procedure was used to quantitate normal immunoglobulins IgG, IgA, and IgM in approximately 300 normal healthy age-defined children. The results were recorded as both, the percentage of the adult level and the Student 2 sample t test to indicate significance of diffe...
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Veröffentlicht in: | Clinica chimica acta 1970-04, Vol.28 (1), p.185-192 |
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description | A modified radial immunodiffusion procedure was used to quantitate normal immunoglobulins IgG, IgA, and IgM in approximately 300 normal healthy age-defined children. The results were recorded as both, the percentage of the adult level and the Student 2 sample
t test to indicate significance of difference from the adult level. Both values were used in our comparisons with other investigators' results. Adult levels of IgM, and IgG were attained at ages of 2 and 7 years, respectively, while IgA was not realized in our studies at the upper age level used, namely 13 years. Comparative increases and decreases of these 3 immunoglobulins over the 13-year span were also discussed. |
doi_str_mv | 10.1016/0009-8981(70)90178-6 |
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t test to indicate significance of difference from the adult level. Both values were used in our comparisons with other investigators' results. Adult levels of IgM, and IgG were attained at ages of 2 and 7 years, respectively, while IgA was not realized in our studies at the upper age level used, namely 13 years. Comparative increases and decreases of these 3 immunoglobulins over the 13-year span were also discussed.</description><identifier>ISSN: 0009-8981</identifier><identifier>EISSN: 1873-3492</identifier><identifier>DOI: 10.1016/0009-8981(70)90178-6</identifier><identifier>PMID: 4191622</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Aging ; Blood Protein Electrophoresis ; Child ; Child, Preschool ; gamma-Globulins - analysis ; Humans ; Immunodiffusion ; Immunoglobulin G - analysis ; Immunoglobulin M - analysis ; Immunoglobulins - analysis ; Infant ; Infant, Newborn ; Statistics as Topic</subject><ispartof>Clinica chimica acta, 1970-04, Vol.28 (1), p.185-192</ispartof><rights>1970</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-a2024eae67b4daa3fca843f157d4bb6fefcb06aa9d3bff21ef8c2b9cf040b9c03</citedby><cites>FETCH-LOGICAL-c357t-a2024eae67b4daa3fca843f157d4bb6fefcb06aa9d3bff21ef8c2b9cf040b9c03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0009898170901786$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4191622$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Uffelman, Jean A.</creatorcontrib><creatorcontrib>Engelhard, Warren E.</creatorcontrib><creatorcontrib>Jolliff, Carl R.</creatorcontrib><title>Quantitation of immunoglobulins in normal children</title><title>Clinica chimica acta</title><addtitle>Clin Chim Acta</addtitle><description>A modified radial immunodiffusion procedure was used to quantitate normal immunoglobulins IgG, IgA, and IgM in approximately 300 normal healthy age-defined children. The results were recorded as both, the percentage of the adult level and the Student 2 sample
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t test to indicate significance of difference from the adult level. Both values were used in our comparisons with other investigators' results. Adult levels of IgM, and IgG were attained at ages of 2 and 7 years, respectively, while IgA was not realized in our studies at the upper age level used, namely 13 years. Comparative increases and decreases of these 3 immunoglobulins over the 13-year span were also discussed.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>4191622</pmid><doi>10.1016/0009-8981(70)90178-6</doi><tpages>8</tpages></addata></record> |
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subjects | Adolescent Adult Aging Blood Protein Electrophoresis Child Child, Preschool gamma-Globulins - analysis Humans Immunodiffusion Immunoglobulin G - analysis Immunoglobulin M - analysis Immunoglobulins - analysis Infant Infant, Newborn Statistics as Topic |
title | Quantitation of immunoglobulins in normal children |
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