Carcinoma of the oesophagus: Factors influencing survival
1 A series of 191 cases of carcinoma of the oesophagus is presented. The 77 cases (middle and lower third) treated by complete oesophagectomy are studied in detail. 2 Evidence for the existence of an immune reaction by the patient against the tumour is found. 3 This immune reaction has a favourable...
Gespeichert in:
| Veröffentlicht in: | British journal of surgery 1970-06, Vol.57 (6), p.422-430 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 430 |
|---|---|
| container_issue | 6 |
| container_start_page | 422 |
| container_title | British journal of surgery |
| container_volume | 57 |
| creator | Younghusband, J. D. Aluwihare, A. P. R. |
| description | 1
A series of 191 cases of carcinoma of the oesophagus is presented. The 77 cases (middle and lower third) treated by complete oesophagectomy are studied in detail.
2
Evidence for the existence of an immune reaction by the patient against the tumour is found.
3
This immune reaction has a favourable effect on the prognosis, even in the presence of other unfavourable features. Delay in diagnosis does not affect the prognosis.
4
It is suggested that the presence of this reaction, as detected by a study of the resected specimen after oesophagectomy, might be used to determine the selective use of post‐operative radiotherapy in an attempt to improve the prognosis in this disease. |
| doi_str_mv | 10.1002/bjs.1800570606 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_84546468</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>84546468</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4346-2051da41f23f0f03008020e0e6e66e63b7678014d170094682f81d53d29e608c3</originalsourceid><addsrcrecordid>eNpFkM1PwkAQxTdGg4hevZn05K04-731po2ghigGDd42S7uFYj-w26L899ZAIJlkMnnvN8l7CF1i6GMAcjNbuj5WAFyCAHGEupgK7hMs1DHqAoD0MSX0FJ05twTAFDjpoA5nFHNJuigITRWlRZkbr0y8emG90rpytTDzxt16AxPVZeW8tEiyxhatce65plqna5Odo5PEZM5e7HYPfQwe3sNHf_Q6fArvRn7EKBM-AY5jw3BCaAIJUAAFBCxYYUU7dCaFVIBZjCVAwIQiicIxpzEJrAAV0R663v5dVeV3Y12t89RFNstMYcvGacU4Ey3XGq92xmaW21ivqjQ31UbvsrZ6sNV_0sxu9jIG_V-kbovUhyL1_fPkcLWsv2VTV9vfPWuqLy0klVxPX4Zavn1OR-Mx1xP6B39xc7k</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>84546468</pqid></control><display><type>article</type><title>Carcinoma of the oesophagus: Factors influencing survival</title><source>MEDLINE</source><source>Wiley Online Library</source><creator>Younghusband, J. D. ; Aluwihare, A. P. R.</creator><creatorcontrib>Younghusband, J. D. ; Aluwihare, A. P. R.</creatorcontrib><description>1
A series of 191 cases of carcinoma of the oesophagus is presented. The 77 cases (middle and lower third) treated by complete oesophagectomy are studied in detail.
2
Evidence for the existence of an immune reaction by the patient against the tumour is found.
3
This immune reaction has a favourable effect on the prognosis, even in the presence of other unfavourable features. Delay in diagnosis does not affect the prognosis.
4
It is suggested that the presence of this reaction, as detected by a study of the resected specimen after oesophagectomy, might be used to determine the selective use of post‐operative radiotherapy in an attempt to improve the prognosis in this disease.</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.1800570606</identifier><identifier>PMID: 5431572</identifier><language>eng</language><publisher>Bristol: John Wiley & Sons, Ltd</publisher><subject>Adenocarcinoma - mortality ; Adult ; Aged ; Carcinoid Tumor - mortality ; Carcinoma, Basal Cell - mortality ; Carcinoma, Squamous Cell - mortality ; Esophageal Neoplasms - immunology ; Esophageal Neoplasms - mortality ; Esophageal Neoplasms - pathology ; Esophageal Neoplasms - radiotherapy ; Esophageal Neoplasms - surgery ; Female ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Prognosis</subject><ispartof>British journal of surgery, 1970-06, Vol.57 (6), p.422-430</ispartof><rights>Copyright © 1970 British Journal of Surgery Society Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4346-2051da41f23f0f03008020e0e6e66e63b7678014d170094682f81d53d29e608c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.1800570606$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.1800570606$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5431572$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Younghusband, J. D.</creatorcontrib><creatorcontrib>Aluwihare, A. P. R.</creatorcontrib><title>Carcinoma of the oesophagus: Factors influencing survival</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>1
A series of 191 cases of carcinoma of the oesophagus is presented. The 77 cases (middle and lower third) treated by complete oesophagectomy are studied in detail.
2
Evidence for the existence of an immune reaction by the patient against the tumour is found.
3
This immune reaction has a favourable effect on the prognosis, even in the presence of other unfavourable features. Delay in diagnosis does not affect the prognosis.
4
It is suggested that the presence of this reaction, as detected by a study of the resected specimen after oesophagectomy, might be used to determine the selective use of post‐operative radiotherapy in an attempt to improve the prognosis in this disease.</description><subject>Adenocarcinoma - mortality</subject><subject>Adult</subject><subject>Aged</subject><subject>Carcinoid Tumor - mortality</subject><subject>Carcinoma, Basal Cell - mortality</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Esophageal Neoplasms - immunology</subject><subject>Esophageal Neoplasms - mortality</subject><subject>Esophageal Neoplasms - pathology</subject><subject>Esophageal Neoplasms - radiotherapy</subject><subject>Esophageal Neoplasms - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prognosis</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1PwkAQxTdGg4hevZn05K04-731po2ghigGDd42S7uFYj-w26L899ZAIJlkMnnvN8l7CF1i6GMAcjNbuj5WAFyCAHGEupgK7hMs1DHqAoD0MSX0FJ05twTAFDjpoA5nFHNJuigITRWlRZkbr0y8emG90rpytTDzxt16AxPVZeW8tEiyxhatce65plqna5Odo5PEZM5e7HYPfQwe3sNHf_Q6fArvRn7EKBM-AY5jw3BCaAIJUAAFBCxYYUU7dCaFVIBZjCVAwIQiicIxpzEJrAAV0R663v5dVeV3Y12t89RFNstMYcvGacU4Ey3XGq92xmaW21ivqjQ31UbvsrZ6sNV_0sxu9jIG_V-kbovUhyL1_fPkcLWsv2VTV9vfPWuqLy0klVxPX4Zavn1OR-Mx1xP6B39xc7k</recordid><startdate>197006</startdate><enddate>197006</enddate><creator>Younghusband, J. D.</creator><creator>Aluwihare, A. P. R.</creator><general>John Wiley & Sons, Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197006</creationdate><title>Carcinoma of the oesophagus: Factors influencing survival</title><author>Younghusband, J. D. ; Aluwihare, A. P. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4346-2051da41f23f0f03008020e0e6e66e63b7678014d170094682f81d53d29e608c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Adenocarcinoma - mortality</topic><topic>Adult</topic><topic>Aged</topic><topic>Carcinoid Tumor - mortality</topic><topic>Carcinoma, Basal Cell - mortality</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Esophageal Neoplasms - immunology</topic><topic>Esophageal Neoplasms - mortality</topic><topic>Esophageal Neoplasms - pathology</topic><topic>Esophageal Neoplasms - radiotherapy</topic><topic>Esophageal Neoplasms - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Younghusband, J. D.</creatorcontrib><creatorcontrib>Aluwihare, A. P. R.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Younghusband, J. D.</au><au>Aluwihare, A. P. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Carcinoma of the oesophagus: Factors influencing survival</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>1970-06</date><risdate>1970</risdate><volume>57</volume><issue>6</issue><spage>422</spage><epage>430</epage><pages>422-430</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><abstract>1
A series of 191 cases of carcinoma of the oesophagus is presented. The 77 cases (middle and lower third) treated by complete oesophagectomy are studied in detail.
2
Evidence for the existence of an immune reaction by the patient against the tumour is found.
3
This immune reaction has a favourable effect on the prognosis, even in the presence of other unfavourable features. Delay in diagnosis does not affect the prognosis.
4
It is suggested that the presence of this reaction, as detected by a study of the resected specimen after oesophagectomy, might be used to determine the selective use of post‐operative radiotherapy in an attempt to improve the prognosis in this disease.</abstract><cop>Bristol</cop><pub>John Wiley & Sons, Ltd</pub><pmid>5431572</pmid><doi>10.1002/bjs.1800570606</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1323 |
| ispartof | British journal of surgery, 1970-06, Vol.57 (6), p.422-430 |
| issn | 0007-1323 1365-2168 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84546468 |
| source | MEDLINE; Wiley Online Library |
| subjects | Adenocarcinoma - mortality Adult Aged Carcinoid Tumor - mortality Carcinoma, Basal Cell - mortality Carcinoma, Squamous Cell - mortality Esophageal Neoplasms - immunology Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophageal Neoplasms - radiotherapy Esophageal Neoplasms - surgery Female Humans Lymphatic Metastasis Male Middle Aged Prognosis |
| title | Carcinoma of the oesophagus: Factors influencing survival |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T18%3A31%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Carcinoma%20of%20the%20oesophagus:%20Factors%20influencing%20survival&rft.jtitle=British%20journal%20of%20surgery&rft.au=Younghusband,%20J.%20D.&rft.date=1970-06&rft.volume=57&rft.issue=6&rft.spage=422&rft.epage=430&rft.pages=422-430&rft.issn=0007-1323&rft.eissn=1365-2168&rft_id=info:doi/10.1002/bjs.1800570606&rft_dat=%3Cproquest_pubme%3E84546468%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=84546468&rft_id=info:pmid/5431572&rfr_iscdi=true |