Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B

Background & Aims Natural killer (NK) cells play a major role in anti-viral immunity as first line defense and regulation of virus-specific T cell responses. This study aimed to investigate phenotype and function of NK cells in patients with chronic hepatitis B virus (HBV) infection and to study...

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Veröffentlicht in:	Journal of hepatology 2011-02, Vol.54 (2), p.209-218
Hauptverfasser:	Tjwa, Eric T.T.L, van Oord, Gertine W, Hegmans, Joost P, Janssen, Harry L.A, Woltman, Andrea M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences CD56 Antigen - analysis CD69 Cross-Sectional Studies Cytotoxicity, Immunologic Entecavir Female Flow Cytometry Gastroenterology and Hepatology Gastroenterology. Liver. Pancreas. Abdomen GPI-Linked Proteins - analysis Guanine - analogs & derivatives Guanine - therapeutic use HBV Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - immunology Hepatitis B, Chronic - virology HLA-DR Antigens - analysis Human viral diseases Humans Infectious diseases Innate immunity Interferon-gamma - biosynthesis Killer Cells, Natural - immunology Lymphocyte Activation Male Medical sciences Natural Cytotoxicity Triggering Receptor 3 - analysis NK Cell Lectin-Like Receptor Subfamily C - analysis NK cells NKG2A Pharmacology. Drug treatments Receptors, IgG - analysis Viral diseases Viral hepatitis Viral Load
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