Radiographic Trabecular Quantitation of Human Lumbar Vertebrae in Situ: I. Theory and Method for Study of Osteoporosis
A scanning microdensitometer-analog computer system is described which permits quantitation of radiographically recorded vertically and horizontally oriented trabecular shadows of in situ human lumbar vertebrae. The basis for vertebral trabecular quantitation in the study of osteoporosis is that tra...
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| Veröffentlicht in: | Invest. Radiol., 2: 272-89(July-Aug. 1967) 2: 272-89(July-Aug. 1967), 1967-07, Vol.2 (4), p.272-289 |
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| container_title | Invest. Radiol., 2: 272-89(July-Aug. 1967) |
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| creator | Rockoff, S David |
| description | A scanning microdensitometer-analog computer system is described which permits quantitation of radiographically recorded vertically and horizontally oriented trabecular shadows of in situ human lumbar vertebrae. The basis for vertebral trabecular quantitation in the study of osteoporosis is that trabecular bone is metabolically more active than is cortical bone and vertebral trabecular bone appears to be the most active trabecular bone of the human body in terms of mineral turnover rate. The method for determining the widths and number of radiographically visualized trabeculae is based upon the observation that, when viewed from the lateral projection, the vertically and horizontally oriented trabeculae have a fairly uniform spatial orientation. The method of quantitation yields data which shows reasonable replication and which appears to reflect the visually assessed character of the trabecular pattern. |
| doi_str_mv | 10.1097/00004424-196707000-00014 |
| format | Article |
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Radiol., 2: 272-89(July-Aug. 1967)</title><addtitle>Invest Radiol</addtitle><description>A scanning microdensitometer-analog computer system is described which permits quantitation of radiographically recorded vertically and horizontally oriented trabecular shadows of in situ human lumbar vertebrae. The basis for vertebral trabecular quantitation in the study of osteoporosis is that trabecular bone is metabolically more active than is cortical bone and vertebral trabecular bone appears to be the most active trabecular bone of the human body in terms of mineral turnover rate. The method for determining the widths and number of radiographically visualized trabeculae is based upon the observation that, when viewed from the lateral projection, the vertically and horizontally oriented trabeculae have a fairly uniform spatial orientation. The method of quantitation yields data which shows reasonable replication and which appears to reflect the visually assessed character of the trabecular pattern.</description><subject>Absorptiometry, Photon</subject><subject>Animals</subject><subject>BONES</subject><subject>Calcification, Physiologic</subject><subject>COMPUTERS</subject><subject>Computers, Analog</subject><subject>COMPUTERS/scanning microdensitometer-analog, design for quantitative x-ray diagnosis of vertebral osteoporosis in man</subject><subject>DENSITOMETERS</subject><subject>DESIGN</subject><subject>DIAGNOSIS</subject><subject>DISEASES</subject><subject>DISEASES, PHYSIOLOGICAL/osteoporosis, radiodiagnosis of vertebral, in man, design of scanning microdensitometer-analog computer system for quantitative x</subject><subject>Humans</subject><subject>Lumbar Vertebrae - analysis</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Lumbar Vertebrae - metabolism</subject><subject>MAN</subject><subject>MAN/ radiodiagnosis of vertebral osteoporosis in, design of scanning microdensitometer- analog computer system for quantitative x</subject><subject>N28530 -Life Sciences-Medicine-Radiodiagnosis</subject><subject>Osteoporosis - diagnostic imaging</subject><subject>Rabbits</subject><subject>RADIATION SOURCES</subject><subject>RADIOGRAPHY, BIOMEDICAL/design of scanning microdensitometer-analog computer system for use in quantitative x-ray, of osteoporosis in man</subject><subject>Technology, Radiologic</subject><issn>0020-9996</issn><issn>1536-0210</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1967</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1rFDEUhgdR6rb6E4TghXdTk0yyM_FOitrCStGu3oZ8nDjRmcmaD8v--2bdtXcGDuHwvuccXp6mQQRfEiz6t7g-xihriVj3uK9dW4uwJ82K8G7dYkrw02aFMcWtEGL9vDlP6We10B53Z83ZGneUCbFq_nxV1ocfUe1Gb9A2Kg2mTCqiL0Ut2WeVfVhQcOi6zGpBmzLrKn6HmEFHBcgv6M7n8g7dXKLtCCHukVos-gx5DBa5ENFdLnZ_2HCbMoRdiCH59KJ55tSU4OXpv2i-ffywvbpuN7efbq7eb1pDD-nMoME5ZZijeg3OUkb0wAkX2uHBcqscr3n6rhN6MBoPSvXWct65DmsmGO8umtfHvSFlL5PxGcxowrKAyZJxKohg1fTmaNrF8LtAynL2ycA0qQVCSXJgnFBBSTUOR6OpIVIEJ3fRzyruJcHywEX-4yIfuci_XOroq9ONomewj4MnEFVnR_0-TBli-jWVe4hyBDXlUf4Pd_cAIEOYiA</recordid><startdate>196707</startdate><enddate>196707</enddate><creator>Rockoff, S David</creator><general>Lippincott-Raven Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>196707</creationdate><title>Radiographic Trabecular Quantitation of Human Lumbar Vertebrae in Situ: I. Theory and Method for Study of Osteoporosis</title><author>Rockoff, S David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2424-c8beffac4f2b6efd241b85159bf08d5daf57037339b8cb08aa7dd553f30b49453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1967</creationdate><topic>Absorptiometry, Photon</topic><topic>Animals</topic><topic>BONES</topic><topic>Calcification, Physiologic</topic><topic>COMPUTERS</topic><topic>Computers, Analog</topic><topic>COMPUTERS/scanning microdensitometer-analog, design for quantitative x-ray diagnosis of vertebral osteoporosis in man</topic><topic>DENSITOMETERS</topic><topic>DESIGN</topic><topic>DIAGNOSIS</topic><topic>DISEASES</topic><topic>DISEASES, PHYSIOLOGICAL/osteoporosis, radiodiagnosis of vertebral, in man, design of scanning microdensitometer-analog computer system for quantitative x</topic><topic>Humans</topic><topic>Lumbar Vertebrae - analysis</topic><topic>Lumbar Vertebrae - diagnostic imaging</topic><topic>Lumbar Vertebrae - metabolism</topic><topic>MAN</topic><topic>MAN/ radiodiagnosis of vertebral osteoporosis in, design of scanning microdensitometer- analog computer system for quantitative x</topic><topic>N28530 -Life Sciences-Medicine-Radiodiagnosis</topic><topic>Osteoporosis - diagnostic imaging</topic><topic>Rabbits</topic><topic>RADIATION SOURCES</topic><topic>RADIOGRAPHY, BIOMEDICAL/design of scanning microdensitometer-analog computer system for use in quantitative x-ray, of osteoporosis in man</topic><topic>Technology, Radiologic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rockoff, S David</creatorcontrib><creatorcontrib>Yale Univ., New Haven</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Invest. Radiol., 2: 272-89(July-Aug. 1967)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rockoff, S David</au><aucorp>Yale Univ., New Haven</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radiographic Trabecular Quantitation of Human Lumbar Vertebrae in Situ: I. Theory and Method for Study of Osteoporosis</atitle><jtitle>Invest. Radiol., 2: 272-89(July-Aug. 1967)</jtitle><addtitle>Invest Radiol</addtitle><date>1967-07</date><risdate>1967</risdate><volume>2</volume><issue>4</issue><spage>272</spage><epage>289</epage><pages>272-289</pages><issn>0020-9996</issn><eissn>1536-0210</eissn><abstract>A scanning microdensitometer-analog computer system is described which permits quantitation of radiographically recorded vertically and horizontally oriented trabecular shadows of in situ human lumbar vertebrae. The basis for vertebral trabecular quantitation in the study of osteoporosis is that trabecular bone is metabolically more active than is cortical bone and vertebral trabecular bone appears to be the most active trabecular bone of the human body in terms of mineral turnover rate. The method for determining the widths and number of radiographically visualized trabeculae is based upon the observation that, when viewed from the lateral projection, the vertically and horizontally oriented trabeculae have a fairly uniform spatial orientation. The method of quantitation yields data which shows reasonable replication and which appears to reflect the visually assessed character of the trabecular pattern.</abstract><cop>United States</cop><pub>Lippincott-Raven Publishers</pub><pmid>6032499</pmid><doi>10.1097/00004424-196707000-00014</doi><tpages>18</tpages></addata></record> |
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| identifier | ISSN: 0020-9996 |
| ispartof | Invest. Radiol., 2: 272-89(July-Aug. 1967), 1967-07, Vol.2 (4), p.272-289 |
| issn | 0020-9996 1536-0210 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Absorptiometry, Photon Animals BONES Calcification, Physiologic COMPUTERS Computers, Analog COMPUTERS/scanning microdensitometer-analog, design for quantitative x-ray diagnosis of vertebral osteoporosis in man DENSITOMETERS DESIGN DIAGNOSIS DISEASES DISEASES, PHYSIOLOGICAL/osteoporosis, radiodiagnosis of vertebral, in man, design of scanning microdensitometer-analog computer system for quantitative x Humans Lumbar Vertebrae - analysis Lumbar Vertebrae - diagnostic imaging Lumbar Vertebrae - metabolism MAN MAN/ radiodiagnosis of vertebral osteoporosis in, design of scanning microdensitometer- analog computer system for quantitative x N28530 -Life Sciences-Medicine-Radiodiagnosis Osteoporosis - diagnostic imaging Rabbits RADIATION SOURCES RADIOGRAPHY, BIOMEDICAL/design of scanning microdensitometer-analog computer system for use in quantitative x-ray, of osteoporosis in man Technology, Radiologic |
| title | Radiographic Trabecular Quantitation of Human Lumbar Vertebrae in Situ: I. Theory and Method for Study of Osteoporosis |
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