Quantitative Determination of Conjugated Bile Acids in Serum in Acute Hepatitis
LITTLE information is available about the variation in concentration of bile acid in serum in health and disease. This is mainly a result of methodological difficulties which result from the solubility of bile acids which closely resembles that of other lipids. Serum extracts prepared according to p...
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| Veröffentlicht in: | Nature (London) 1967-01, Vol.213 (5074), p.404-405 |
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| creator | FROSCH, B. WAGENER, H. |
| description | LITTLE information is available about the variation in concentration of bile acid in serum in health and disease. This is mainly a result of methodological difficulties which result from the solubility of bile acids which closely resembles that of other lipids. Serum extracts prepared according to previous techniques often contain small quantities of lipid material which cause errors in the assay of bile acids
1
. Attempts to separate these interfering substances are often associated with considerable losses of bile acids. These difficulties explain discrepancies in values for the concentration of normal bile acid in serum which have been reported to range between 0 and 60 mg/ml.
2
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| doi_str_mv | 10.1038/213404a0 |
| format | Article |
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1
. Attempts to separate these interfering substances are often associated with considerable losses of bile acids. These difficulties explain discrepancies in values for the concentration of normal bile acid in serum which have been reported to range between 0 and 60 mg/ml.
2
.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/213404a0</identifier><identifier>PMID: 6029533</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Bile Acids and Salts - blood ; Bilirubin - blood ; Chromatography, Thin Layer ; Hepatitis - blood ; Humanities and Social Sciences ; Humans ; letter ; multidisciplinary ; Science ; Science (multidisciplinary) ; Transaminases - blood</subject><ispartof>Nature (London), 1967-01, Vol.213 (5074), p.404-405</ispartof><rights>Springer Nature Limited 1967</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c312t-442510170fad5c01e8a284727c0fedee52d74e024b6674c2f0394bfbfc2425ac3</citedby><cites>FETCH-LOGICAL-c312t-442510170fad5c01e8a284727c0fedee52d74e024b6674c2f0394bfbfc2425ac3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/213404a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/213404a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6029533$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FROSCH, B.</creatorcontrib><creatorcontrib>WAGENER, H.</creatorcontrib><title>Quantitative Determination of Conjugated Bile Acids in Serum in Acute Hepatitis</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>LITTLE information is available about the variation in concentration of bile acid in serum in health and disease. This is mainly a result of methodological difficulties which result from the solubility of bile acids which closely resembles that of other lipids. Serum extracts prepared according to previous techniques often contain small quantities of lipid material which cause errors in the assay of bile acids
1
. Attempts to separate these interfering substances are often associated with considerable losses of bile acids. These difficulties explain discrepancies in values for the concentration of normal bile acid in serum which have been reported to range between 0 and 60 mg/ml.
2
.</description><subject>Bile Acids and Salts - blood</subject><subject>Bilirubin - blood</subject><subject>Chromatography, Thin Layer</subject><subject>Hepatitis - blood</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Transaminases - blood</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1967</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkFtLAzEQhYMotVbBPyDkSfRhdZLN3h5rvVQoFFGfl2x2VlK62ZqL4L83pdUXn2aG850Dcwg5Z3DDIC1vOUsFCAkHZMxEkSciL4tDMgbgZQJlmh-TE-dWAJCxQozIKAdeZWk6JsuXII3XXnr9hfQePdpem3gNhg4dnQ1mFT6kx5be6TXSqdKto9rQV7Sh3y5TFTzSOW6ix2t3So46uXZ4tp8T8v748DabJ4vl0_NsukhUyrhPhOAZA1ZAJ9tMAcNS8lIUvFDQYYuY8bYQCFw0eV4IxTtIK9F0Tad4dEqVTsjlLndjh8-Azte9dgrXa2lwCK4uhaiqPKsieLUDlR2cs9jVG6t7ab9rBvW2u_q3u4he7DND02P7B-7Livr1TndRMR9o69UQrIlv_s_6AUf3dWw</recordid><startdate>19670128</startdate><enddate>19670128</enddate><creator>FROSCH, B.</creator><creator>WAGENER, H.</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19670128</creationdate><title>Quantitative Determination of Conjugated Bile Acids in Serum in Acute Hepatitis</title><author>FROSCH, B. ; WAGENER, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c312t-442510170fad5c01e8a284727c0fedee52d74e024b6674c2f0394bfbfc2425ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1967</creationdate><topic>Bile Acids and Salts - blood</topic><topic>Bilirubin - blood</topic><topic>Chromatography, Thin Layer</topic><topic>Hepatitis - blood</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Transaminases - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FROSCH, B.</creatorcontrib><creatorcontrib>WAGENER, H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FROSCH, B.</au><au>WAGENER, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantitative Determination of Conjugated Bile Acids in Serum in Acute Hepatitis</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1967-01-28</date><risdate>1967</risdate><volume>213</volume><issue>5074</issue><spage>404</spage><epage>405</epage><pages>404-405</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>LITTLE information is available about the variation in concentration of bile acid in serum in health and disease. This is mainly a result of methodological difficulties which result from the solubility of bile acids which closely resembles that of other lipids. Serum extracts prepared according to previous techniques often contain small quantities of lipid material which cause errors in the assay of bile acids
1
. Attempts to separate these interfering substances are often associated with considerable losses of bile acids. These difficulties explain discrepancies in values for the concentration of normal bile acid in serum which have been reported to range between 0 and 60 mg/ml.
2
.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>6029533</pmid><doi>10.1038/213404a0</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1967-01, Vol.213 (5074), p.404-405 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals; Nature Journals Online |
| subjects | Bile Acids and Salts - blood Bilirubin - blood Chromatography, Thin Layer Hepatitis - blood Humanities and Social Sciences Humans letter multidisciplinary Science Science (multidisciplinary) Transaminases - blood |
| title | Quantitative Determination of Conjugated Bile Acids in Serum in Acute Hepatitis |
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