Resistance of Mycoplasma pneumoniae to erythromycin and other antibiotics
A case is reported of a 14-year-old girl who had M. pneumoniae pneumonia, and in whom the resistance of the organism increased suddently from a minimal inhibitory concentration of erythromycin of 0.008 to 400 γ per milliliter 2 weeks after the beginning of erythromycin therapy. At the same time the...
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| Veröffentlicht in: | The Journal of pediatrics 1970-03, Vol.76 (3), p.438-443 |
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| container_end_page | 443 |
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| container_issue | 3 |
| container_start_page | 438 |
| container_title | The Journal of pediatrics |
| container_volume | 76 |
| creator | Niitu, Yasutaka Hasegawa, Sumio Suetake, Tomiko Kubota, Hideo Komatsu, Shigeo Horikawa, Masahiro |
| description | A case is reported of a 14-year-old girl who had
M. pneumoniae pneumonia, and in whom the resistance of the organism increased suddently from a minimal inhibitory concentration of erythromycin of 0.008 to 400 γ per milliliter 2 weeks after the beginning of erythromycin therapy. At the same time the organism developed resistance to oleandomycin, spiramycin, leucomycin, josamycin, and lincomycin. The clinical course was uneventful in spite of the emergence of resistance; the radiologic findings returned to normal 3 weeks after the beginning of erythromycin therapy. |
| doi_str_mv | 10.1016/S0022-3476(70)80485-1 |
| format | Article |
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M. pneumoniae pneumonia, and in whom the resistance of the organism increased suddently from a minimal inhibitory concentration of erythromycin of 0.008 to 400 γ per milliliter 2 weeks after the beginning of erythromycin therapy. At the same time the organism developed resistance to oleandomycin, spiramycin, leucomycin, josamycin, and lincomycin. 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M. pneumoniae pneumonia, and in whom the resistance of the organism increased suddently from a minimal inhibitory concentration of erythromycin of 0.008 to 400 γ per milliliter 2 weeks after the beginning of erythromycin therapy. At the same time the organism developed resistance to oleandomycin, spiramycin, leucomycin, josamycin, and lincomycin. The clinical course was uneventful in spite of the emergence of resistance; the radiologic findings returned to normal 3 weeks after the beginning of erythromycin therapy.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>5413664</pmid><doi>10.1016/S0022-3476(70)80485-1</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adolescent Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Complement Fixation Tests Drug Resistance, Microbial Erythromycin - pharmacology Female Fermentation Hemagglutination Tests Humans Leucomycins - pharmacology Lincomycin - pharmacology Microbial Sensitivity Tests Mycoplasma - drug effects Mycoplasma - immunology Mycoplasma - isolation & purification Mycoplasma Infections - diagnostic imaging Mycoplasma Infections - drug therapy Oleandomycin - pharmacology Radiography |
| title | Resistance of Mycoplasma pneumoniae to erythromycin and other antibiotics |
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