The morphologic development of the sinoatrial node in the mouse
A plastic embedding technique was employed on mouse embryos after fixation with a gluteraldehyde-paraformaldehyde mixture and preparation of large, 1 to 2 μ sections cut on a rotary microtome with steel knives. It was then possible to trace the sinoatrial node back to mouse embryos of 4 sol1 2 mm cr...
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| Veröffentlicht in: | The American journal of cardiology 1970-02, Vol.25 (2), p.204-212 |
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| container_title | The American journal of cardiology |
| container_volume | 25 |
| creator | Van Mierop, L.H.S. Gessner, Ira H. |
| description | A plastic embedding technique was employed on mouse embryos after fixation with a gluteraldehyde-paraformaldehyde mixture and preparation of large, 1 to 2 μ sections cut on a rotary microtome with steel knives. It was then possible to trace the sinoatrial node back to mouse embryos of
4
sol1
2
mm
crown-rump length (
10
1
2
days
gestational age, corresponding developmentally to 6 mm human embryos). In the mouse, the sinoatrial node lies anteromedially just above the cavoatrial junction. The nodal artery, which is located more or less centrally, is a branch of the internal mammary artery, not of the coronary arterial system. Even in the youngest embryos examined thus far, the node is strictly unilateral in structure. |
| doi_str_mv | 10.1016/0002-9149(70)90580-1 |
| format | Article |
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4
sol1
2
mm
crown-rump length (
10
1
2
days
gestational age, corresponding developmentally to 6 mm human embryos). In the mouse, the sinoatrial node lies anteromedially just above the cavoatrial junction. The nodal artery, which is located more or less centrally, is a branch of the internal mammary artery, not of the coronary arterial system. Even in the youngest embryos examined thus far, the node is strictly unilateral in structure.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/0002-9149(70)90580-1</identifier><identifier>PMID: 4905014</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Animals, Newborn ; Female ; Gestational Age ; Histological Techniques ; Mice ; Microtomy ; Morphogenesis ; Pregnancy ; Sinoatrial Node - anatomy & histology ; Sinoatrial Node - embryology ; Sinoatrial Node - growth & development ; Thoracic Arteries - embryology</subject><ispartof>The American journal of cardiology, 1970-02, Vol.25 (2), p.204-212</ispartof><rights>1970</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c272t-cfa0af209f12e9c78865eea114cbbc23d8ca47050b7cae6ee7e7b7b7cb3f3c463</citedby><cites>FETCH-LOGICAL-c272t-cfa0af209f12e9c78865eea114cbbc23d8ca47050b7cae6ee7e7b7b7cb3f3c463</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0002914970905801$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4905014$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Van Mierop, L.H.S.</creatorcontrib><creatorcontrib>Gessner, Ira H.</creatorcontrib><title>The morphologic development of the sinoatrial node in the mouse</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>A plastic embedding technique was employed on mouse embryos after fixation with a gluteraldehyde-paraformaldehyde mixture and preparation of large, 1 to 2 μ sections cut on a rotary microtome with steel knives. It was then possible to trace the sinoatrial node back to mouse embryos of
4
sol1
2
mm
crown-rump length (
10
1
2
days
gestational age, corresponding developmentally to 6 mm human embryos). In the mouse, the sinoatrial node lies anteromedially just above the cavoatrial junction. The nodal artery, which is located more or less centrally, is a branch of the internal mammary artery, not of the coronary arterial system. Even in the youngest embryos examined thus far, the node is strictly unilateral in structure.</description><subject>Animals</subject><subject>Animals, Newborn</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Histological Techniques</subject><subject>Mice</subject><subject>Microtomy</subject><subject>Morphogenesis</subject><subject>Pregnancy</subject><subject>Sinoatrial Node - anatomy & histology</subject><subject>Sinoatrial Node - embryology</subject><subject>Sinoatrial Node - growth & development</subject><subject>Thoracic Arteries - embryology</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EKqXwByBlhWAR8CRuHG9AqOIlVWJT1pbjjKlREgc7rcTf4z7UJfLC8tw7d8aHkEugd0ChuKeUZqkAJm44vRV0WtIUjsgYSi5SEJAfk_HBckrOQviOT4BpMSIjFv0U2Jg8LpaYtM73S9e4L6uTGtfYuL7FbkicSYYoB9s5NXirmqRzNSa225Zbtwp4Tk6MagJe7O8J-Xx5Xsze0vnH6_vsaZ7qjGdDqo2iymRUGMhQaF6WxRRRATBdVTrL61IrxuNOFdcKC0SOvIpHV7nJNSvyCbne5fbe_awwDLK1QWPTqA7jHrJkrBAZ0GhkO6P2LgSPRvbetsr_SqByw01uoMgNFMmp3HKTENuu9vmrqsX60LQHFfWHnY7xk2uLXgZtsdNYW496kLWz_w_4AxoefNQ</recordid><startdate>197002</startdate><enddate>197002</enddate><creator>Van Mierop, L.H.S.</creator><creator>Gessner, Ira H.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197002</creationdate><title>The morphologic development of the sinoatrial node in the mouse</title><author>Van Mierop, L.H.S. ; Gessner, Ira H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c272t-cfa0af209f12e9c78865eea114cbbc23d8ca47050b7cae6ee7e7b7b7cb3f3c463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Animals</topic><topic>Animals, Newborn</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Histological Techniques</topic><topic>Mice</topic><topic>Microtomy</topic><topic>Morphogenesis</topic><topic>Pregnancy</topic><topic>Sinoatrial Node - anatomy & histology</topic><topic>Sinoatrial Node - embryology</topic><topic>Sinoatrial Node - growth & development</topic><topic>Thoracic Arteries - embryology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Van Mierop, L.H.S.</creatorcontrib><creatorcontrib>Gessner, Ira H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Van Mierop, L.H.S.</au><au>Gessner, Ira H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The morphologic development of the sinoatrial node in the mouse</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1970-02</date><risdate>1970</risdate><volume>25</volume><issue>2</issue><spage>204</spage><epage>212</epage><pages>204-212</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><abstract>A plastic embedding technique was employed on mouse embryos after fixation with a gluteraldehyde-paraformaldehyde mixture and preparation of large, 1 to 2 μ sections cut on a rotary microtome with steel knives. It was then possible to trace the sinoatrial node back to mouse embryos of
4
sol1
2
mm
crown-rump length (
10
1
2
days
gestational age, corresponding developmentally to 6 mm human embryos). In the mouse, the sinoatrial node lies anteromedially just above the cavoatrial junction. The nodal artery, which is located more or less centrally, is a branch of the internal mammary artery, not of the coronary arterial system. Even in the youngest embryos examined thus far, the node is strictly unilateral in structure.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>4905014</pmid><doi>10.1016/0002-9149(70)90580-1</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 1970-02, Vol.25 (2), p.204-212 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84469210 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Animals, Newborn Female Gestational Age Histological Techniques Mice Microtomy Morphogenesis Pregnancy Sinoatrial Node - anatomy & histology Sinoatrial Node - embryology Sinoatrial Node - growth & development Thoracic Arteries - embryology |
| title | The morphologic development of the sinoatrial node in the mouse |
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