Plasmodium berghei Dihydrofolate Reductase Isolation, Properties, and Inhibition by Antifolates
Dihydrofolate reductase has been isolated from cells of the rodent malarial organism Plasmodium berghei by separation from the host cells with saponin and extraction by rupture in a French pressure cell. The enzyme exhibits certain distinctive properties which clearly distinguish it from the dihydro...
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Veröffentlicht in: | Molecular pharmacology 1969-01, Vol.5 (1), p.49-59 |
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Sprache: | eng |
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