Suppressive effect of Petasites japonicus extract on ovalbumin-induced airway inflammation in an asthmatic mouse model

Petasites japonicus extract has inhibitory properties on asthma and may be used as a potent therapeutic agent for allergic lung inflammation. Asthma is a disease marked by airway inflammation. Petasites japonicus (Pj) is known as an herb for treating asthma, oxidant stress and gastric ulcer in tradi...

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Veröffentlicht in:	Journal of ethnopharmacology 2011-01, Vol.133 (2), p.551-557
Hauptverfasser:	Lee, Ji-Sook, Yang, Eun Ju, Yun, Chi-Young, Kim, Dong-Hee, Kim, In Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway inflammation animal models Animals Anti-Asthmatic Agents - isolation & purification Anti-Asthmatic Agents - pharmacology Anti-Asthmatic Agents - toxicity anti-inflammatory activity Anti-inflammatory effect antioxidant activity asthma Asthma - drug therapy Asthma - etiology Asthma - pathology Asthma - physiopathology Biological and medical sciences bronchoalveolar lavage fluid Cell Line chemokines cytokines Cytokines - metabolism cytotoxicity Disease Models, Animal Eosinophils Ethnopharmacology Female General pharmacology Humans immunoglobulin E Immunoglobulin E - blood inflammation interleukin-5 Jurkat Cells leukocytes Lung - drug effects Lung - pathology Medical sciences medicinal plants Medicine, Korean Traditional Mice Mice, Inbred BALB C mucus mucus hypersecretion Ovalbumin - immunology pathogenesis Petasites - chemistry Petasites japonicus Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy plant extracts Plant Extracts - pharmacology Plant Extracts - toxicity protective effect reactive oxygen species Reactive Oxygen Species - metabolism respiratory system
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