Hemoglobin Richmond, a Human Hemoglobin Which Forms Asymmetric Hybrids with Other Hemoglobins

The discovery of an abnormal hemoglobin variant (hemoglobin Richmond) in several members of a Negro family is reported. Structural analyses indicated a replacement of asparaginyl residue G4(102)Î² by a lysyl residue, while no other abnormality has been found. Carriers of this hemoglobin abnormality...

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Veröffentlicht in:	The Journal of biological chemistry 1969-11, Vol.244 (22), p.6105-6116
Hauptverfasser:	Efremov, G D, Huisman, T H, Smith, L L, Wilson, J B, Kitchens, J L, Wrightstone, R N, Adams, H R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult African Americans Amino Acid Sequence Amino Acids - analysis Asparagine Blood Protein Electrophoresis Buffers Child Chromatography, Ion Exchange Edetic Acid Genes Hemoglobins, Abnormal - analysis Humans Hybridization, Genetic Hydrogen-Ion Concentration Lysine Middle Aged Pedigree Peptides - isolation & purification Sodium Chloride Ultracentrifugation
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