In Vitro studies with "Transfer Factor": Transfer of the Cell-Migration Inhibition Correlate of Delayed Hypersensitivity in Humans with Cell Lysates from Humans Sensitized to Histoplasmin, Coccidioidin, or PPD
When “nonsensitive” cells from skin test negative donors were incubated with specific antigen and specific cell lysates obtained from strongly skin test-positive histoplasmin, coccidioidin, or tuberculin skin test donors, the “nonsensitive” cells were “sensitized” and liberated a substance which spe...
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| Veröffentlicht in: | The Journal of immunology (1950) 1969-11, Vol.103 (5), p.1014-1021 |
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| container_end_page | 1021 |
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| container_issue | 5 |
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| container_title | The Journal of immunology (1950) |
| container_volume | 103 |
| creator | Paque, Ronald E Kniskern, Peter J Dray, Sheldon Baram, Peter |
| description | When “nonsensitive” cells from skin test negative donors were incubated with specific antigen and specific cell lysates obtained from strongly skin test-positive histoplasmin, coccidioidin, or tuberculin skin test donors, the “nonsensitive” cells were “sensitized” and liberated a substance which specifically inhibited the migration of guinea pig macrophages. Cell lysates, antigen, or nonspecific combinations of both, either in the presence or absence of “nonsensitive” cells, failed to inhibit the migration of guinea pig macrophages. |
| doi_str_mv | 10.4049/jimmunol.103.5.1014 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0022-1767 |
| ispartof | The Journal of immunology (1950), 1969-11, Vol.103 (5), p.1014-1021 |
| issn | 0022-1767 1550-6606 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84290192 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Cell Movement Coccidioides - immunology Culture Techniques Histoplasmin Humans Hypersensitivity, Delayed - immunology Leukocytes - immunology Macrophages - immunology RNA Skin Tests Tissue Extracts Tuberculin |
| title | In Vitro studies with "Transfer Factor": Transfer of the Cell-Migration Inhibition Correlate of Delayed Hypersensitivity in Humans with Cell Lysates from Humans Sensitized to Histoplasmin, Coccidioidin, or PPD |
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