Demonstration of protein-losing gastroenteropathy the disappearance rate of 51Cr from plasma and the binding of 51Cr to different serum proteins
The application of 51Cr-labelled plasma proteins for the detection of proteinlosing gastroenteropathy has important advantages over the use of 131I-albumin or 131I-PVP. The disappearance of 51Cr from the plasma after intravenous administration was found to be almost identical, irrespective of whethe...
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| Veröffentlicht in: | Clinica chimica acta 1966-07, Vol.14 (1), p.31-41 |
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| container_title | Clinica chimica acta |
| container_volume | 14 |
| creator | Van Tongeren, J.H.M. Majoor, C.L.H. |
| description | The application of
51Cr-labelled plasma proteins for the detection of proteinlosing gastroenteropathy has important advantages over the use of
131I-albumin or
131I-PVP. The disappearance of
51Cr from the plasma after intravenous administration was found to be almost identical, irrespective of whether a self-prepared
51Cr-albumin, a good commercial preparation of
51Cr-albumin,
51Cr-serum or
51CrCl
3 were used. The excretion in the urine of
51Cr presented no remarkable differences after administration of
51Cr-albumin,
51Cr-serum or
51CrCl
3. The much faster disappearance of
51Cr from the plasma, after injection of
51Cr-albumin, as compared to
131I after administration of
131I-albumin is probably not due to denaturation of albumin, but to the fact that
51Cr shifts from albumin to other plasma proteins, especially to transferrin. |
| doi_str_mv | 10.1016/0009-8981(66)90061-1 |
| format | Article |
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51Cr-labelled plasma proteins for the detection of proteinlosing gastroenteropathy has important advantages over the use of
131I-albumin or
131I-PVP. The disappearance of
51Cr from the plasma after intravenous administration was found to be almost identical, irrespective of whether a self-prepared
51Cr-albumin, a good commercial preparation of
51Cr-albumin,
51Cr-serum or
51CrCl
3 were used. The excretion in the urine of
51Cr presented no remarkable differences after administration of
51Cr-albumin,
51Cr-serum or
51CrCl
3. The much faster disappearance of
51Cr from the plasma, after injection of
51Cr-albumin, as compared to
131I after administration of
131I-albumin is probably not due to denaturation of albumin, but to the fact that
51Cr shifts from albumin to other plasma proteins, especially to transferrin.</description><identifier>ISSN: 0009-8981</identifier><identifier>EISSN: 1873-3492</identifier><identifier>DOI: 10.1016/0009-8981(66)90061-1</identifier><identifier>PMID: 5958730</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Blood Protein Electrophoresis ; Blood Proteins ; Chromium Isotopes - blood ; Chromium Isotopes - urine ; Humans ; Protein Binding ; Protein-Losing Enteropathies - blood ; Serum Albumin - analysis ; Serum Albumin, Radio-Iodinated ; Ultracentrifugation</subject><ispartof>Clinica chimica acta, 1966-07, Vol.14 (1), p.31-41</ispartof><rights>1966</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c289t-c623dee8efa593f809d9246e8fa0302c41ef1e65631fcc73010c870503de09e3</citedby><cites>FETCH-LOGICAL-c289t-c623dee8efa593f809d9246e8fa0302c41ef1e65631fcc73010c870503de09e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0009-8981(66)90061-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5958730$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Van Tongeren, J.H.M.</creatorcontrib><creatorcontrib>Majoor, C.L.H.</creatorcontrib><title>Demonstration of protein-losing gastroenteropathy the disappearance rate of 51Cr from plasma and the binding of 51Cr to different serum proteins</title><title>Clinica chimica acta</title><addtitle>Clin Chim Acta</addtitle><description>The application of
51Cr-labelled plasma proteins for the detection of proteinlosing gastroenteropathy has important advantages over the use of
131I-albumin or
131I-PVP. The disappearance of
51Cr from the plasma after intravenous administration was found to be almost identical, irrespective of whether a self-prepared
51Cr-albumin, a good commercial preparation of
51Cr-albumin,
51Cr-serum or
51CrCl
3 were used. The excretion in the urine of
51Cr presented no remarkable differences after administration of
51Cr-albumin,
51Cr-serum or
51CrCl
3. The much faster disappearance of
51Cr from the plasma, after injection of
51Cr-albumin, as compared to
131I after administration of
131I-albumin is probably not due to denaturation of albumin, but to the fact that
51Cr shifts from albumin to other plasma proteins, especially to transferrin.</description><subject>Blood Protein Electrophoresis</subject><subject>Blood Proteins</subject><subject>Chromium Isotopes - blood</subject><subject>Chromium Isotopes - urine</subject><subject>Humans</subject><subject>Protein Binding</subject><subject>Protein-Losing Enteropathies - blood</subject><subject>Serum Albumin - analysis</subject><subject>Serum Albumin, Radio-Iodinated</subject><subject>Ultracentrifugation</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1OAyEUhYnR1Fp9A01YGV2MwvxQ2JiY-puYuHFPKHNRzAyMQE36Fj6yjK0uXRFyv3NO7rkIHVNyQQlll4QQUXDB6Rlj54IQRgu6g6aUz6uiqkW5i6Z_yD46iPE9f-uMTdCkEU3GyBR93UDvXUxBJesd9gYPwSewruh8tO4Vv6o89OASBD-o9LbG6Q1wa6MaBlBBOQ04i2GUNnQRsAm-x0OnYq-wcu0PvrSuHc1-meSzgzEQsi-OEFb9b2w8RHtGdRGOtu8Mvdzdviweiqfn-8fF9VOhSy5SoVlZtQAcjGpEZTgRrShrBtwoUpFS1xQMBdawihqt86qUaD4nDckqIqCaodONbc79WEFMsrdRQ9cpB34VJa_LedXwOoP1BtTBxxjAyCHYXoW1pESOd5BjyXIsWTImf-4gaZadbP1Xyx7aP9G2-Dy_2swh7_hpIcioLeQyWxtAJ9l6-3_AN2eKmXo</recordid><startdate>196607</startdate><enddate>196607</enddate><creator>Van Tongeren, J.H.M.</creator><creator>Majoor, C.L.H.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196607</creationdate><title>Demonstration of protein-losing gastroenteropathy the disappearance rate of 51Cr from plasma and the binding of 51Cr to different serum proteins</title><author>Van Tongeren, J.H.M. ; Majoor, C.L.H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c289t-c623dee8efa593f809d9246e8fa0302c41ef1e65631fcc73010c870503de09e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><topic>Blood Protein Electrophoresis</topic><topic>Blood Proteins</topic><topic>Chromium Isotopes - blood</topic><topic>Chromium Isotopes - urine</topic><topic>Humans</topic><topic>Protein Binding</topic><topic>Protein-Losing Enteropathies - blood</topic><topic>Serum Albumin - analysis</topic><topic>Serum Albumin, Radio-Iodinated</topic><topic>Ultracentrifugation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Van Tongeren, J.H.M.</creatorcontrib><creatorcontrib>Majoor, C.L.H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Van Tongeren, J.H.M.</au><au>Majoor, C.L.H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Demonstration of protein-losing gastroenteropathy the disappearance rate of 51Cr from plasma and the binding of 51Cr to different serum proteins</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1966-07</date><risdate>1966</risdate><volume>14</volume><issue>1</issue><spage>31</spage><epage>41</epage><pages>31-41</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><abstract>The application of
51Cr-labelled plasma proteins for the detection of proteinlosing gastroenteropathy has important advantages over the use of
131I-albumin or
131I-PVP. The disappearance of
51Cr from the plasma after intravenous administration was found to be almost identical, irrespective of whether a self-prepared
51Cr-albumin, a good commercial preparation of
51Cr-albumin,
51Cr-serum or
51CrCl
3 were used. The excretion in the urine of
51Cr presented no remarkable differences after administration of
51Cr-albumin,
51Cr-serum or
51CrCl
3. The much faster disappearance of
51Cr from the plasma, after injection of
51Cr-albumin, as compared to
131I after administration of
131I-albumin is probably not due to denaturation of albumin, but to the fact that
51Cr shifts from albumin to other plasma proteins, especially to transferrin.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>5958730</pmid><doi>10.1016/0009-8981(66)90061-1</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-8981 |
| ispartof | Clinica chimica acta, 1966-07, Vol.14 (1), p.31-41 |
| issn | 0009-8981 1873-3492 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84273584 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Blood Protein Electrophoresis Blood Proteins Chromium Isotopes - blood Chromium Isotopes - urine Humans Protein Binding Protein-Losing Enteropathies - blood Serum Albumin - analysis Serum Albumin, Radio-Iodinated Ultracentrifugation |
| title | Demonstration of protein-losing gastroenteropathy the disappearance rate of 51Cr from plasma and the binding of 51Cr to different serum proteins |
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