Malformations of the central nervous system in trisomy 18 syndrome
Malformations of the central nervous system in trisomy 18 are relatively uncommon as compared with trisomy 13 (D 1), but may nevertheless be part of the phenotypic manifestation of trisomy 18. Anomalies of the central nervous system observed in trisomy 18 have included: meningoencephalocele, hydroce...
Gespeichert in:
| Veröffentlicht in: | The Journal of pediatrics 1966-11, Vol.69 (5), p.771-778 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 778 |
|---|---|
| container_issue | 5 |
| container_start_page | 771 |
| container_title | The Journal of pediatrics |
| container_volume | 69 |
| creator | Passarge, Eberhard True, Charles W. Sueoka, William T. Baumgartner, Nicholas R. Keer, Kenneth R. |
| description | Malformations of the central nervous system in trisomy 18 are relatively uncommon as compared with trisomy 13 (D
1), but may nevertheless be part of the phenotypic manifestation of trisomy 18. Anomalies of the central nervous system observed in trisomy 18 have included: meningoencephalocele, hydrocephalus, prosencephaly, absent corpus callosum, defective falx cerebri, and abnormal cerebellum. A lumbar meningocele was observed in two infants described here, in one of whom there was also a strikingly abnormal brain with malformed gyri, absent occipital lobe, and defective optic tracts. The malformations of the central nervous system observed in the trisomy 18 syndrome are reviewed and summarized in a table. |
| doi_str_mv | 10.1016/S0022-3476(66)80123-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_84254396</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022347666801233</els_id><sourcerecordid>84254396</sourcerecordid><originalsourceid>FETCH-LOGICAL-c426t-de59e38975411a3b8134aa37d19f881625868b031ebafa17c156ddf820f586db3</originalsourceid><addsrcrecordid>eNqFkEtLAzEUhYMotVZ_QiEr0cVoMpnJZFaixRdUXKjrkEluMDIzqUla6L93-qBbVxfuOec-PoSmlNxQQvntByF5nrGi4lecXwtCc5axIzSmpK4yLhg7RuOD5RSdxfhDCKkLQkZoVNa5IESM0cObaq0PnUrO9xF7i9M3YA19CqrFPYSVX0Yc1zFBh12PU3DRd2tMxdDsTfAdnKMTq9oIF_s6QV9Pj5-zl2z-_vw6u59nush5ygyUNTBRV2VBqWKNoKxQilWG1lYIyvNScNEQRqFRVtFK05IbY0VO7KCYhk3Q5W7uIvjfJcQkOxc1tK3qYThSiiIvC1bzwVjujDr4GANYuQiuU2EtKZEbdnLLTm7ASM7llp1kQ266X7BsOjCH1B7WoN_tdBi-XDkIMmoHvQbjAugkjXf_bPgDKzR9hg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>84254396</pqid></control><display><type>article</type><title>Malformations of the central nervous system in trisomy 18 syndrome</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Passarge, Eberhard ; True, Charles W. ; Sueoka, William T. ; Baumgartner, Nicholas R. ; Keer, Kenneth R.</creator><creatorcontrib>Passarge, Eberhard ; True, Charles W. ; Sueoka, William T. ; Baumgartner, Nicholas R. ; Keer, Kenneth R.</creatorcontrib><description>Malformations of the central nervous system in trisomy 18 are relatively uncommon as compared with trisomy 13 (D
1), but may nevertheless be part of the phenotypic manifestation of trisomy 18. Anomalies of the central nervous system observed in trisomy 18 have included: meningoencephalocele, hydrocephalus, prosencephaly, absent corpus callosum, defective falx cerebri, and abnormal cerebellum. A lumbar meningocele was observed in two infants described here, in one of whom there was also a strikingly abnormal brain with malformed gyri, absent occipital lobe, and defective optic tracts. The malformations of the central nervous system observed in the trisomy 18 syndrome are reviewed and summarized in a table.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/S0022-3476(66)80123-3</identifier><identifier>PMID: 5928008</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Adult ; Brain - abnormalities ; Cytogenetics ; Dermatoglyphics ; Female ; Humans ; Infant, Newborn ; Male ; Meningocele - etiology ; Middle Aged ; Pregnancy ; Trisomy - complications</subject><ispartof>The Journal of pediatrics, 1966-11, Vol.69 (5), p.771-778</ispartof><rights>1966 The C. V. Mosby Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-de59e38975411a3b8134aa37d19f881625868b031ebafa17c156ddf820f586db3</citedby><cites>FETCH-LOGICAL-c426t-de59e38975411a3b8134aa37d19f881625868b031ebafa17c156ddf820f586db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0022-3476(66)80123-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5928008$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Passarge, Eberhard</creatorcontrib><creatorcontrib>True, Charles W.</creatorcontrib><creatorcontrib>Sueoka, William T.</creatorcontrib><creatorcontrib>Baumgartner, Nicholas R.</creatorcontrib><creatorcontrib>Keer, Kenneth R.</creatorcontrib><title>Malformations of the central nervous system in trisomy 18 syndrome</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Malformations of the central nervous system in trisomy 18 are relatively uncommon as compared with trisomy 13 (D
1), but may nevertheless be part of the phenotypic manifestation of trisomy 18. Anomalies of the central nervous system observed in trisomy 18 have included: meningoencephalocele, hydrocephalus, prosencephaly, absent corpus callosum, defective falx cerebri, and abnormal cerebellum. A lumbar meningocele was observed in two infants described here, in one of whom there was also a strikingly abnormal brain with malformed gyri, absent occipital lobe, and defective optic tracts. The malformations of the central nervous system observed in the trisomy 18 syndrome are reviewed and summarized in a table.</description><subject>Adult</subject><subject>Brain - abnormalities</subject><subject>Cytogenetics</subject><subject>Dermatoglyphics</subject><subject>Female</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Meningocele - etiology</subject><subject>Middle Aged</subject><subject>Pregnancy</subject><subject>Trisomy - complications</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotVZ_QiEr0cVoMpnJZFaixRdUXKjrkEluMDIzqUla6L93-qBbVxfuOec-PoSmlNxQQvntByF5nrGi4lecXwtCc5axIzSmpK4yLhg7RuOD5RSdxfhDCKkLQkZoVNa5IESM0cObaq0PnUrO9xF7i9M3YA19CqrFPYSVX0Yc1zFBh12PU3DRd2tMxdDsTfAdnKMTq9oIF_s6QV9Pj5-zl2z-_vw6u59nush5ygyUNTBRV2VBqWKNoKxQilWG1lYIyvNScNEQRqFRVtFK05IbY0VO7KCYhk3Q5W7uIvjfJcQkOxc1tK3qYThSiiIvC1bzwVjujDr4GANYuQiuU2EtKZEbdnLLTm7ASM7llp1kQ266X7BsOjCH1B7WoN_tdBi-XDkIMmoHvQbjAugkjXf_bPgDKzR9hg</recordid><startdate>196611</startdate><enddate>196611</enddate><creator>Passarge, Eberhard</creator><creator>True, Charles W.</creator><creator>Sueoka, William T.</creator><creator>Baumgartner, Nicholas R.</creator><creator>Keer, Kenneth R.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196611</creationdate><title>Malformations of the central nervous system in trisomy 18 syndrome</title><author>Passarge, Eberhard ; True, Charles W. ; Sueoka, William T. ; Baumgartner, Nicholas R. ; Keer, Kenneth R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-de59e38975411a3b8134aa37d19f881625868b031ebafa17c156ddf820f586db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><topic>Adult</topic><topic>Brain - abnormalities</topic><topic>Cytogenetics</topic><topic>Dermatoglyphics</topic><topic>Female</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Meningocele - etiology</topic><topic>Middle Aged</topic><topic>Pregnancy</topic><topic>Trisomy - complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Passarge, Eberhard</creatorcontrib><creatorcontrib>True, Charles W.</creatorcontrib><creatorcontrib>Sueoka, William T.</creatorcontrib><creatorcontrib>Baumgartner, Nicholas R.</creatorcontrib><creatorcontrib>Keer, Kenneth R.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Passarge, Eberhard</au><au>True, Charles W.</au><au>Sueoka, William T.</au><au>Baumgartner, Nicholas R.</au><au>Keer, Kenneth R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malformations of the central nervous system in trisomy 18 syndrome</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>1966-11</date><risdate>1966</risdate><volume>69</volume><issue>5</issue><spage>771</spage><epage>778</epage><pages>771-778</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>Malformations of the central nervous system in trisomy 18 are relatively uncommon as compared with trisomy 13 (D
1), but may nevertheless be part of the phenotypic manifestation of trisomy 18. Anomalies of the central nervous system observed in trisomy 18 have included: meningoencephalocele, hydrocephalus, prosencephaly, absent corpus callosum, defective falx cerebri, and abnormal cerebellum. A lumbar meningocele was observed in two infants described here, in one of whom there was also a strikingly abnormal brain with malformed gyri, absent occipital lobe, and defective optic tracts. The malformations of the central nervous system observed in the trisomy 18 syndrome are reviewed and summarized in a table.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>5928008</pmid><doi>10.1016/S0022-3476(66)80123-3</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3476 |
| ispartof | The Journal of pediatrics, 1966-11, Vol.69 (5), p.771-778 |
| issn | 0022-3476 1097-6833 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84254396 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adult Brain - abnormalities Cytogenetics Dermatoglyphics Female Humans Infant, Newborn Male Meningocele - etiology Middle Aged Pregnancy Trisomy - complications |
| title | Malformations of the central nervous system in trisomy 18 syndrome |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T01%3A26%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Malformations%20of%20the%20central%20nervous%20system%20in%20trisomy%2018%20syndrome&rft.jtitle=The%20Journal%20of%20pediatrics&rft.au=Passarge,%20Eberhard&rft.date=1966-11&rft.volume=69&rft.issue=5&rft.spage=771&rft.epage=778&rft.pages=771-778&rft.issn=0022-3476&rft.eissn=1097-6833&rft_id=info:doi/10.1016/S0022-3476(66)80123-3&rft_dat=%3Cproquest_cross%3E84254396%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=84254396&rft_id=info:pmid/5928008&rft_els_id=S0022347666801233&rfr_iscdi=true |