Adrenal Response to Excess Corticotropin in Coronary-Prone Men
Summary The adrenal response to excess corticotropin (achieved either by its administration or by metyrapone-induced excess endogenous secretion) was found to be significantly reduced in the majority of individuals assessed as relatively prone to future incidence of clinical coronary heart disease w...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1969-09, Vol.131 (4), p.1305-1307 |
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| Sprache: | eng |
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| container_end_page | 1307 |
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| container_issue | 4 |
| container_start_page | 1305 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 131 |
| creator | Friedman, Meyer Rosenman, Ray H. St. George, Shirley |
| description | Summary
The adrenal response to excess corticotropin (achieved either by its administration or by metyrapone-induced excess endogenous secretion) was found to be significantly reduced in the majority of individuals assessed as relatively prone to future incidence of clinical coronary heart disease when compared with the adrenal response of subjects believed to be relatively immune to the occurrence of the same disorder. |
| doi_str_mv | 10.3181/00379727-131-34093 |
| format | Article |
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The adrenal response to excess corticotropin (achieved either by its administration or by metyrapone-induced excess endogenous secretion) was found to be significantly reduced in the majority of individuals assessed as relatively prone to future incidence of clinical coronary heart disease when compared with the adrenal response of subjects believed to be relatively immune to the occurrence of the same disorder.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-131-34093</identifier><identifier>PMID: 4309476</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>17-Hydroxycorticosteroids - urine ; Adrenal Glands - drug effects ; Adrenal Glands - physiology ; Adrenocorticotropic Hormone - metabolism ; Adrenocorticotropic Hormone - pharmacology ; Adult ; Coronary Disease ; Disease Susceptibility ; Drive ; Humans ; Male ; Metyrapone - pharmacology ; Middle Aged ; Pituitary-Adrenal System ; Stimulation, Chemical ; Stress, Psychological</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1969-09, Vol.131 (4), p.1305-1307</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-6ef53891b19d66b914d387c144a24e04705637f3fa8c9a46bf0a839d6080879d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4309476$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Friedman, Meyer</creatorcontrib><creatorcontrib>Rosenman, Ray H.</creatorcontrib><creatorcontrib>St. George, Shirley</creatorcontrib><title>Adrenal Response to Excess Corticotropin in Coronary-Prone Men</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
The adrenal response to excess corticotropin (achieved either by its administration or by metyrapone-induced excess endogenous secretion) was found to be significantly reduced in the majority of individuals assessed as relatively prone to future incidence of clinical coronary heart disease when compared with the adrenal response of subjects believed to be relatively immune to the occurrence of the same disorder.</description><subject>17-Hydroxycorticosteroids - urine</subject><subject>Adrenal Glands - drug effects</subject><subject>Adrenal Glands - physiology</subject><subject>Adrenocorticotropic Hormone - metabolism</subject><subject>Adrenocorticotropic Hormone - pharmacology</subject><subject>Adult</subject><subject>Coronary Disease</subject><subject>Disease Susceptibility</subject><subject>Drive</subject><subject>Humans</subject><subject>Male</subject><subject>Metyrapone - pharmacology</subject><subject>Middle Aged</subject><subject>Pituitary-Adrenal System</subject><subject>Stimulation, Chemical</subject><subject>Stress, Psychological</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1969</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUhoMoc07_gCD0yru4pCfNx40gY37ARBG9DmmaSkfX1KQF_fdmbnopHDhwznNekgehc0qugEo6JwSEErnAFCgGRhQcoCktoMDAlTpE0y2At8QxOolxTQgtRM4naMKAKCb4FF3fVMF1ps1eXOx9F102-Gz5aV2M2cKHobF-CL5vuixVGvjOhC_8nLrLHl13io5q00Z3tu8z9Ha7fF3c49XT3cPiZoUtgBwwd3UBUtGSqorzUlFWgRSWMmZy5ggTpOAgaqiNtMowXtbESEgskUQKVcEMXe5y--A_RhcHvWmidW1rOufHqCXLc54-lMB8B9rgYwyu1n1oNunNmhK9laZ_pekkTf9IS0cX-_Sx3Ljq72RvKe3nu300706v_RiSsfhf4jfH2nM9</recordid><startdate>196909</startdate><enddate>196909</enddate><creator>Friedman, Meyer</creator><creator>Rosenman, Ray H.</creator><creator>St. George, Shirley</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196909</creationdate><title>Adrenal Response to Excess Corticotropin in Coronary-Prone Men</title><author>Friedman, Meyer ; Rosenman, Ray H. ; St. George, Shirley</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-6ef53891b19d66b914d387c144a24e04705637f3fa8c9a46bf0a839d6080879d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1969</creationdate><topic>17-Hydroxycorticosteroids - urine</topic><topic>Adrenal Glands - drug effects</topic><topic>Adrenal Glands - physiology</topic><topic>Adrenocorticotropic Hormone - metabolism</topic><topic>Adrenocorticotropic Hormone - pharmacology</topic><topic>Adult</topic><topic>Coronary Disease</topic><topic>Disease Susceptibility</topic><topic>Drive</topic><topic>Humans</topic><topic>Male</topic><topic>Metyrapone - pharmacology</topic><topic>Middle Aged</topic><topic>Pituitary-Adrenal System</topic><topic>Stimulation, Chemical</topic><topic>Stress, Psychological</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Friedman, Meyer</creatorcontrib><creatorcontrib>Rosenman, Ray H.</creatorcontrib><creatorcontrib>St. George, Shirley</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Friedman, Meyer</au><au>Rosenman, Ray H.</au><au>St. George, Shirley</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adrenal Response to Excess Corticotropin in Coronary-Prone Men</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1969-09</date><risdate>1969</risdate><volume>131</volume><issue>4</issue><spage>1305</spage><epage>1307</epage><pages>1305-1307</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
The adrenal response to excess corticotropin (achieved either by its administration or by metyrapone-induced excess endogenous secretion) was found to be significantly reduced in the majority of individuals assessed as relatively prone to future incidence of clinical coronary heart disease when compared with the adrenal response of subjects believed to be relatively immune to the occurrence of the same disorder.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>4309476</pmid><doi>10.3181/00379727-131-34093</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1969-09, Vol.131 (4), p.1305-1307 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84226476 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | 17-Hydroxycorticosteroids - urine Adrenal Glands - drug effects Adrenal Glands - physiology Adrenocorticotropic Hormone - metabolism Adrenocorticotropic Hormone - pharmacology Adult Coronary Disease Disease Susceptibility Drive Humans Male Metyrapone - pharmacology Middle Aged Pituitary-Adrenal System Stimulation, Chemical Stress, Psychological |
| title | Adrenal Response to Excess Corticotropin in Coronary-Prone Men |
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