Optical behavior of indocyanine green dye in blood and in aqueous solution
Indocyanine green dye in the presence of sodium bisulfite exhibits a marked and extremely variable decrease in light absorption. Even the presence of the extremely minute quantity present in Lipo-Hepin, when used as an anticoagulant, will vitiate densitometer calibration. Spectrophotometric studies...
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| Veröffentlicht in: | The American heart journal 1966-09, Vol.72 (3), p.345-350 |
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| container_title | The American heart journal |
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| creator | Sutterer, William F. Hardin, Schuyler E. Benson, Robert W. Jerome Krovetz, L. Schiebler, Gerold L. |
| description | Indocyanine green dye in the presence of sodium bisulfite exhibits a marked and extremely variable decrease in light absorption. Even the presence of the extremely minute quantity present in Lipo-Hepin, when used as an anticoagulant, will vitiate densitometer calibration.
Spectrophotometric studies of aqueous solutions of dye in the presence of Lipo-Hepin do not show a marked change in light absorption of the dye. Stronger solutions of sodium bisulfite produced a marked decrease in light absorption over these wave lengths.
Indocyanine green dye kept in a concentrated aqueous solution for periods up to 7 days shifts its peak absorption from 780 to 900 m
μ. This shift in peak absorption is probably due to reversible polymolecular aggregation.
As previously reported, fresh solutions of indocyanine green in plasma have an absorption maximum at 800 m
μ. Peak absorption of aged dye-plasma solutions remains at 900 m
μ. |
| doi_str_mv | 10.1016/S0002-8703(66)80008-X |
| format | Article |
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Spectrophotometric studies of aqueous solutions of dye in the presence of Lipo-Hepin do not show a marked change in light absorption of the dye. Stronger solutions of sodium bisulfite produced a marked decrease in light absorption over these wave lengths.
Indocyanine green dye kept in a concentrated aqueous solution for periods up to 7 days shifts its peak absorption from 780 to 900 m
μ. This shift in peak absorption is probably due to reversible polymolecular aggregation.
As previously reported, fresh solutions of indocyanine green in plasma have an absorption maximum at 800 m
μ. Peak absorption of aged dye-plasma solutions remains at 900 m
μ.</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/S0002-8703(66)80008-X</identifier><identifier>PMID: 5331210</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Coloring Agents - blood ; Densitometry ; Dye Dilution Technique ; Humans ; Indocyanine Green ; Sodium ; Solutions ; Sulfites</subject><ispartof>The American heart journal, 1966-09, Vol.72 (3), p.345-350</ispartof><rights>1966 The C. V. Mosby Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-50c63d6a506e1534cb4e5d3ca404f09a9ec88bfe090bc62eadd504ce99d048d83</citedby><cites>FETCH-LOGICAL-c360t-50c63d6a506e1534cb4e5d3ca404f09a9ec88bfe090bc62eadd504ce99d048d83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S000287036680008X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5331210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sutterer, William F.</creatorcontrib><creatorcontrib>Hardin, Schuyler E.</creatorcontrib><creatorcontrib>Benson, Robert W.</creatorcontrib><creatorcontrib>Jerome Krovetz, L.</creatorcontrib><creatorcontrib>Schiebler, Gerold L.</creatorcontrib><title>Optical behavior of indocyanine green dye in blood and in aqueous solution</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>Indocyanine green dye in the presence of sodium bisulfite exhibits a marked and extremely variable decrease in light absorption. Even the presence of the extremely minute quantity present in Lipo-Hepin, when used as an anticoagulant, will vitiate densitometer calibration.
Spectrophotometric studies of aqueous solutions of dye in the presence of Lipo-Hepin do not show a marked change in light absorption of the dye. Stronger solutions of sodium bisulfite produced a marked decrease in light absorption over these wave lengths.
Indocyanine green dye kept in a concentrated aqueous solution for periods up to 7 days shifts its peak absorption from 780 to 900 m
μ. This shift in peak absorption is probably due to reversible polymolecular aggregation.
As previously reported, fresh solutions of indocyanine green in plasma have an absorption maximum at 800 m
μ. Peak absorption of aged dye-plasma solutions remains at 900 m
μ.</description><subject>Coloring Agents - blood</subject><subject>Densitometry</subject><subject>Dye Dilution Technique</subject><subject>Humans</subject><subject>Indocyanine Green</subject><subject>Sodium</subject><subject>Solutions</subject><subject>Sulfites</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EKqXwCZWyQrAITGLHdVYIVTxVqQtA6s5y7AkYpXaxk0r9e9KH2LIa3Zk7r0PIOIObDDJ--wYAeSomQK84vxa9EuniiAwzKCcpnzB2TIZ_llNyFuN3L3ku-IAMCkqzPIMheZ2vWqtVk1T4pdbWh8TXiXXG641y1mHyGRBdYjbYZ5Oq8d4kypmtUD8d-i4m0Tdda707Jye1aiJeHOKIfDw-vE-f09n86WV6P0s15dCmBWhODVcFcMwKynTFsDBUKwashlKVqIWoaoQSKs1zVMYUwDSWpQEmjKAjcrmfuwq-PyG2cmmjxqZRbnuPFCyHIgfaG4u9UQcfY8BaroJdqrCRGcgtQ7ljKLeAJOdyx1Au-r7xYUFXLdH8dR2g9fW7fR37L9cWg4zaotNobEDdSuPtPxt-AXKugVQ</recordid><startdate>196609</startdate><enddate>196609</enddate><creator>Sutterer, William F.</creator><creator>Hardin, Schuyler E.</creator><creator>Benson, Robert W.</creator><creator>Jerome Krovetz, L.</creator><creator>Schiebler, Gerold L.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196609</creationdate><title>Optical behavior of indocyanine green dye in blood and in aqueous solution</title><author>Sutterer, William F. ; Hardin, Schuyler E. ; Benson, Robert W. ; Jerome Krovetz, L. ; Schiebler, Gerold L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-50c63d6a506e1534cb4e5d3ca404f09a9ec88bfe090bc62eadd504ce99d048d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><topic>Coloring Agents - blood</topic><topic>Densitometry</topic><topic>Dye Dilution Technique</topic><topic>Humans</topic><topic>Indocyanine Green</topic><topic>Sodium</topic><topic>Solutions</topic><topic>Sulfites</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sutterer, William F.</creatorcontrib><creatorcontrib>Hardin, Schuyler E.</creatorcontrib><creatorcontrib>Benson, Robert W.</creatorcontrib><creatorcontrib>Jerome Krovetz, L.</creatorcontrib><creatorcontrib>Schiebler, Gerold L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sutterer, William F.</au><au>Hardin, Schuyler E.</au><au>Benson, Robert W.</au><au>Jerome Krovetz, L.</au><au>Schiebler, Gerold L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optical behavior of indocyanine green dye in blood and in aqueous solution</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>1966-09</date><risdate>1966</risdate><volume>72</volume><issue>3</issue><spage>345</spage><epage>350</epage><pages>345-350</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><abstract>Indocyanine green dye in the presence of sodium bisulfite exhibits a marked and extremely variable decrease in light absorption. Even the presence of the extremely minute quantity present in Lipo-Hepin, when used as an anticoagulant, will vitiate densitometer calibration.
Spectrophotometric studies of aqueous solutions of dye in the presence of Lipo-Hepin do not show a marked change in light absorption of the dye. Stronger solutions of sodium bisulfite produced a marked decrease in light absorption over these wave lengths.
Indocyanine green dye kept in a concentrated aqueous solution for periods up to 7 days shifts its peak absorption from 780 to 900 m
μ. This shift in peak absorption is probably due to reversible polymolecular aggregation.
As previously reported, fresh solutions of indocyanine green in plasma have an absorption maximum at 800 m
μ. Peak absorption of aged dye-plasma solutions remains at 900 m
μ.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>5331210</pmid><doi>10.1016/S0002-8703(66)80008-X</doi><tpages>6</tpages></addata></record> |
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| ispartof | The American heart journal, 1966-09, Vol.72 (3), p.345-350 |
| issn | 0002-8703 1097-6744 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Coloring Agents - blood Densitometry Dye Dilution Technique Humans Indocyanine Green Sodium Solutions Sulfites |
| title | Optical behavior of indocyanine green dye in blood and in aqueous solution |
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