Similarities between the pharmacological actions of quipazine and serotonin

Experiments have been carried out to establish possible similarities between the actions of quipazine, 2-(1-Piperazinyl) quinoline maleate, a smooth muscle stimulant, and serotonin. When tested on diverse structures, quipazine was found to elicit effects similar to those of serotonin. Thus, it stimu...

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Veröffentlicht in:	European journal of pharmacology 1969-01, Vol.6 (3), p.274-280
Hauptverfasser:	Hong, Enrique, Sancilio, Lawrence F., Vargas, Roberto, Pardo, Efraín G.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-(1-Piperazinyl)quinoline Animals Aorta - drug effects Behavior, Animal - drug effects Bronchi - drug effects Constriction Cyproheptadine - pharmacology Edema - chemically induced Female Guinea Pigs Ileum - drug effects Lung - drug effects Lysergic Acid Diethylamide - pharmacology Methysergide - pharmacology Morphine - pharmacology Muscle Contraction - drug effects Muscle, Smooth - drug effects Phenoxybenzamine - pharmacology Quinolines - pharmacology Quinolizines - antagonists & inhibitors Quipazine maleate Rabbits Rats Serotonin - pharmacology Serotonin like actions Smooth muscle stimulants Trachea - drug effects Uterus - drug effects
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