Chloric acid digestion in the determination of trace metals (Fe, Zn and Cu) in brain and hair by atomic absorption spectrophotometry
A simple chloric acid digestion technique for tissue and subsequent quantitation of Fe, Zn and Cu in the digest by atomic absorption spectrophotometry is described. The digestion is carried out in a heating block, requires little attention and permits the handling of large numbers of samples. The di...
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Veröffentlicht in: | Clinica chimica acta 1969-05, Vol.24 (2), p.233-238 |
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description | A simple chloric acid digestion technique for tissue and subsequent quantitation of Fe, Zn and Cu in the digest by atomic absorption spectrophotometry is described. The digestion is carried out in a heating block, requires little attention and permits the handling of large numbers of samples. The diluted digest is used for direct analysis of Fe, Zn and Cu. For low concentrations of Cu, solvent extraction of the digest is employed and Cu is assayed in the organic phase. The precision of the technique for the determination of Fe, Zn and Cu in brain tissue and hair is presented. |
doi_str_mv | 10.1016/0009-8981(69)90318-0 |
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The digestion is carried out in a heating block, requires little attention and permits the handling of large numbers of samples. The diluted digest is used for direct analysis of Fe, Zn and Cu. For low concentrations of Cu, solvent extraction of the digest is employed and Cu is assayed in the organic phase. The precision of the technique for the determination of Fe, Zn and Cu in brain tissue and hair is presented.</description><identifier>ISSN: 0009-8981</identifier><identifier>EISSN: 1873-3492</identifier><identifier>DOI: 10.1016/0009-8981(69)90318-0</identifier><identifier>PMID: 5787326</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Acids ; Brain Chemistry ; Chemistry, Clinical - standards ; Copper - analysis ; Hair - analysis ; Humans ; Iron - analysis ; Methods ; Solubility ; Specimen Handling ; Spectrum Analysis ; Zinc - analysis</subject><ispartof>Clinica chimica acta, 1969-05, Vol.24 (2), p.233-238</ispartof><rights>1969</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c272t-d1bac087df2a1483985aa13156849cdd921e79676167a7c2793af85df0978113</citedby><cites>FETCH-LOGICAL-c272t-d1bac087df2a1483985aa13156849cdd921e79676167a7c2793af85df0978113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0009-8981(69)90318-0$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5787326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Backer, E.T.</creatorcontrib><title>Chloric acid digestion in the determination of trace metals (Fe, Zn and Cu) in brain and hair by atomic absorption spectrophotometry</title><title>Clinica chimica acta</title><addtitle>Clin Chim Acta</addtitle><description>A simple chloric acid digestion technique for tissue and subsequent quantitation of Fe, Zn and Cu in the digest by atomic absorption spectrophotometry is described. The digestion is carried out in a heating block, requires little attention and permits the handling of large numbers of samples. The diluted digest is used for direct analysis of Fe, Zn and Cu. For low concentrations of Cu, solvent extraction of the digest is employed and Cu is assayed in the organic phase. The precision of the technique for the determination of Fe, Zn and Cu in brain tissue and hair is presented.</description><subject>Acids</subject><subject>Brain Chemistry</subject><subject>Chemistry, Clinical - standards</subject><subject>Copper - analysis</subject><subject>Hair - analysis</subject><subject>Humans</subject><subject>Iron - analysis</subject><subject>Methods</subject><subject>Solubility</subject><subject>Specimen Handling</subject><subject>Spectrum Analysis</subject><subject>Zinc - analysis</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1969</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVJSLZp_0EDOpUE6kRje_VxCZSlaQOBXHLKRcjSuKuytlxJW9h7fnjl3SXHnITm_RjmIeQLsBtgwG8ZY6qSSsIVV9eKNSAr9oEsQIqmalpVn5DFm-WcfEzpT_m2jMMZOVuK4qr5gryu1psQvaXGeked_40p-zBSP9K8RuowYxz8aPbD0NMcjUU6YDabRK_u8Rt9GakZHV1tr-dQF40_DNbGR9rtqMlhmPu7FOK0r0kT2hzDtA5Fwhx3n8hpX_rw8_G9IM_3P55Xv6rHp58Pq--Pla1FnSsHnbFMCtfXBlrZKLk0BhpYctkq65yqAYXiggMXRpSMakwvl65nSkiA5oJ8PdROMfzdlkP14JPFzcaMGLZJyxZEw6EtxvZgtDGkFLHXU_SDiTsNTM_s9QxWz2A1V3rPXrMSuzz2b7sB3VvoCLvodwcdy43_PEadrMfRovOxENEu-PcX_AfN75N3</recordid><startdate>196905</startdate><enddate>196905</enddate><creator>Backer, E.T.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196905</creationdate><title>Chloric acid digestion in the determination of trace metals (Fe, Zn and Cu) in brain and hair by atomic absorption spectrophotometry</title><author>Backer, E.T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c272t-d1bac087df2a1483985aa13156849cdd921e79676167a7c2793af85df0978113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1969</creationdate><topic>Acids</topic><topic>Brain Chemistry</topic><topic>Chemistry, Clinical - standards</topic><topic>Copper - analysis</topic><topic>Hair - analysis</topic><topic>Humans</topic><topic>Iron - analysis</topic><topic>Methods</topic><topic>Solubility</topic><topic>Specimen Handling</topic><topic>Spectrum Analysis</topic><topic>Zinc - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Backer, E.T.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Backer, E.T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chloric acid digestion in the determination of trace metals (Fe, Zn and Cu) in brain and hair by atomic absorption spectrophotometry</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1969-05</date><risdate>1969</risdate><volume>24</volume><issue>2</issue><spage>233</spage><epage>238</epage><pages>233-238</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><abstract>A simple chloric acid digestion technique for tissue and subsequent quantitation of Fe, Zn and Cu in the digest by atomic absorption spectrophotometry is described. The digestion is carried out in a heating block, requires little attention and permits the handling of large numbers of samples. The diluted digest is used for direct analysis of Fe, Zn and Cu. For low concentrations of Cu, solvent extraction of the digest is employed and Cu is assayed in the organic phase. The precision of the technique for the determination of Fe, Zn and Cu in brain tissue and hair is presented.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>5787326</pmid><doi>10.1016/0009-8981(69)90318-0</doi><tpages>6</tpages></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Acids Brain Chemistry Chemistry, Clinical - standards Copper - analysis Hair - analysis Humans Iron - analysis Methods Solubility Specimen Handling Spectrum Analysis Zinc - analysis |
title | Chloric acid digestion in the determination of trace metals (Fe, Zn and Cu) in brain and hair by atomic absorption spectrophotometry |
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