Dihydroorotic Acid Dehydrogenase: Introduction into Erythrocyte by the Malaria Parasite

Dihydroorotic Acid Dehydrogenase: Introduction into Erythrocyte by the Malaria Parasite

Mature, circulating mammalian erythrocytes lack dihydroorotic acid dehydrogenase activity. However, we have detected activity, which appears to reside in an enzyme, in malaria parasites purified from mammalian blood.

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Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1969-05, Vol.164 (3883), p.1073-1075
Hauptverfasser: Krooth, Robert S., Wuu, Kuang-Dong, Ma, Raymond
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Blood
Catalytic activity
Dehydrogenases
Dialysis
Enzymes
Erythrocytes
Erythrocytes - enzymology
Infections
Malaria
Malaria - blood
Mice
Orotic Acid - metabolism
Oxidoreductases - blood
Parasite hosts
Parasites
Plasmodium - enzymology
Rats
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Beschreibung
Zusammenfassung:Mature, circulating mammalian erythrocytes lack dihydroorotic acid dehydrogenase activity. However, we have detected activity, which appears to reside in an enzyme, in malaria parasites purified from mammalian blood.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.164.3883.1073