The effects of 5-bromodeoxyuridine on the differentiation of chondrocytes in vitro

BUdR at low levels (10 −7 M) can completely but reversibly inhibit the expression of differentiation by chondrocytes grown as single cell derived clones in a modification of Ham's medium F10. The effect of BUdR can be reversed by thymidine and uridine. Uridine itself stimulates differentiation,...

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Veröffentlicht in:	Developmental biology 1969-05, Vol.19 (5), p.415-435
Hauptverfasser:	Lasher, Robert, Cahn, Robert D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bromodeoxyuridine - antagonists & inhibitors Bromodeoxyuridine - pharmacology Cartilage - embryology Cell Differentiation - drug effects Chick Embryo Clone Cells In Vitro Techniques Mutation Thymidine - pharmacology Uridine - pharmacology
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