The Modification of Yeast Hexokinases by Proteases and Its Relationship to the Dissociation of Hexokinase into Subunits

Crystalline hexokinase prepared by the method of Darrow and Colowick consists largely of enzyme which has been modified in its chromatographic and electrophoretic behavior by yeast protease which is present during the isolation procedure. This proteolytic modification can be prevented by removal of...

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