Validity of indicator-dilution determinations of cardiac output in patients with mitral regurgitation
A total of 532 groups of indicator-dilution determinations of cardiac index were performed in four groups of patients, many with mitral regurgitation. The indicator, indocyanine green, was injected into the right atrium and sampled from both the pulmonary and systemic arterial trees. The potential p...
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| Veröffentlicht in: | Circulation (New York, N.Y.) N.Y.), 1966-03, Vol.33 (3), p.410-416 |
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| container_end_page | 416 |
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| container_title | Circulation (New York, N.Y.) |
| container_volume | 33 |
| creator | Samet, P Bernstein, W H Castillo, C |
| description | A total of 532 groups of indicator-dilution determinations of cardiac index were performed in four groups of patients, many with mitral regurgitation. The indicator, indocyanine green, was injected into the right atrium and sampled from both the pulmonary and systemic arterial trees. The potential problem imposed by early recirculation of indicator particles was present in the latter but not the former dilution curves. The absence of physiologically significant differences between the two sampling sites demonstrates that even severe mitral regurgitation does not vitiate indicator-dilution determination of cardiac output after right heart injection and systemic arterial sampling if the downstroke of the primary dilution curve permits a straight line semilogarithmic extrapolation. |
| doi_str_mv | 10.1161/01.CIR.33.3.410 |
| format | Article |
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The absence of physiologically significant differences between the two sampling sites demonstrates that even severe mitral regurgitation does not vitiate indicator-dilution determination of cardiac output after right heart injection and systemic arterial sampling if the downstroke of the primary dilution curve permits a straight line semilogarithmic extrapolation.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/01.CIR.33.3.410</identifier><identifier>PMID: 5323926</identifier><language>eng</language><publisher>United States</publisher><subject>Blood Circulation ; Cardiac Output ; Dye Dilution Technique ; Humans ; Mitral Valve Insufficiency</subject><ispartof>Circulation (New York, N.Y.), 1966-03, Vol.33 (3), p.410-416</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c373t-3f95e5bc435d6274f0b3d42cc99a5e1d726e681b01b9343f3cd090cdaf0fa3063</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,3687,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5323926$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Samet, P</creatorcontrib><creatorcontrib>Bernstein, W H</creatorcontrib><creatorcontrib>Castillo, C</creatorcontrib><title>Validity of indicator-dilution determinations of cardiac output in patients with mitral regurgitation</title><title>Circulation (New York, N.Y.)</title><addtitle>Circulation</addtitle><description>A total of 532 groups of indicator-dilution determinations of cardiac index were performed in four groups of patients, many with mitral regurgitation. The indicator, indocyanine green, was injected into the right atrium and sampled from both the pulmonary and systemic arterial trees. The potential problem imposed by early recirculation of indicator particles was present in the latter but not the former dilution curves. The absence of physiologically significant differences between the two sampling sites demonstrates that even severe mitral regurgitation does not vitiate indicator-dilution determination of cardiac output after right heart injection and systemic arterial sampling if the downstroke of the primary dilution curve permits a straight line semilogarithmic extrapolation.</description><subject>Blood Circulation</subject><subject>Cardiac Output</subject><subject>Dye Dilution Technique</subject><subject>Humans</subject><subject>Mitral Valve Insufficiency</subject><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLAzEURoMotVbXroSs3M00yZ3MmKUUH4WCIOo2ZPKokXnUJIP03ztji6vLxz3fhXsQuqYkp7SkS0Lz1fo1B8ghLyg5QXPKWZEVHMQpmhNCRFYBY-foIsavMZZQ8RmacWAgWDlH9kM13vi0x73DvjNeq9SHzPhmSL7vsLHJhtZ3akpxgrQKxiuN-yHthjR28G5c2i5F_OPTJ259CqrBwW6HsPXpr3iJzpxqor06zgV6f3x4Wz1nm5en9ep-k2moIGXgBLe81gVwU7KqcKQGUzCthVDcUlOx0pZ3tCa0FlCAA22IINooR5yC8bcFuj3c3YX-e7AxydZHbZtGdbYforwbFQEwMYLLA6hDH2OwTu6Cb1XYS0rkJFYSKkexEkCCnFoLdHM8PdStNf_80ST8Amr3deY</recordid><startdate>196603</startdate><enddate>196603</enddate><creator>Samet, P</creator><creator>Bernstein, W H</creator><creator>Castillo, C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196603</creationdate><title>Validity of indicator-dilution determinations of cardiac output in patients with mitral regurgitation</title><author>Samet, P ; Bernstein, W H ; Castillo, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c373t-3f95e5bc435d6274f0b3d42cc99a5e1d726e681b01b9343f3cd090cdaf0fa3063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><topic>Blood Circulation</topic><topic>Cardiac Output</topic><topic>Dye Dilution Technique</topic><topic>Humans</topic><topic>Mitral Valve Insufficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Samet, P</creatorcontrib><creatorcontrib>Bernstein, W H</creatorcontrib><creatorcontrib>Castillo, C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Samet, P</au><au>Bernstein, W H</au><au>Castillo, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Validity of indicator-dilution determinations of cardiac output in patients with mitral regurgitation</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><addtitle>Circulation</addtitle><date>1966-03</date><risdate>1966</risdate><volume>33</volume><issue>3</issue><spage>410</spage><epage>416</epage><pages>410-416</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><abstract>A total of 532 groups of indicator-dilution determinations of cardiac index were performed in four groups of patients, many with mitral regurgitation. 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| fulltext | fulltext |
| identifier | ISSN: 0009-7322 |
| ispartof | Circulation (New York, N.Y.), 1966-03, Vol.33 (3), p.410-416 |
| issn | 0009-7322 1524-4539 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84103329 |
| source | MEDLINE; American Heart Association Journals; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | Blood Circulation Cardiac Output Dye Dilution Technique Humans Mitral Valve Insufficiency |
| title | Validity of indicator-dilution determinations of cardiac output in patients with mitral regurgitation |
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