DNA Replication Kinetics in X-Irradiated Chinese Hamster Ovary Cells

The kinetics of semiconservative DNA replication have been studied in both asynchronous and synchronized Chinese hamster ovary cells (CHO) irradiated with X-ray doses up to 3000 rad. Amounts of DNA replicated were determined by isopycnic gradient centrifugation of DNA from cells which were incubated...

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Bibliographische Detailangaben
Veröffentlicht in:	Radiat. Res.; (United States) 1977-08, Vol.71 (2), p.387-397
1. Verfasser:	Gerner, Eugene W.
Format:	Artikel
Sprache:	eng
Schlagworte:	560121 - Radiation Effects on Cells- External Source- (-1987) ANIMAL CELLS ANIMALS ANTIMETABOLITES ANTIMITOTIC DRUGS AZINES BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BIOSYNTHESIS BROMOURACILS BUDR CELL CULTURES Cell lines Cells, Cultured - radiation effects CHO cells Cultured cells DNA REPLICATION DNA Replication - radiation effects DOSE-RESPONSE RELATIONSHIPS DRUGS ELECTROMAGNETIC RADIATION FLUOROURACILS FUDR HAMSTERS HeLa cells HETEROCYCLIC COMPOUNDS HYDROXY COMPOUNDS Interphase IONIZING RADIATIONS Irradiation Kinetics L cells MAMMALS Mitosis Mitosis - radiation effects NUCLEIC ACID REPLICATION NUCLEOSIDES NUCLEOTIDES ORGANIC BROMINE COMPOUNDS ORGANIC COMPOUNDS ORGANIC FLUORINE COMPOUNDS ORGANIC HALOGEN COMPOUNDS ORGANIC NITROGEN COMPOUNDS PYRIMIDINES RADIATION EFFECTS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIATIONS RADIOSENSITIVITY EFFECTS RADIOSENSITIZERS RESPONSE MODIFYING FACTORS RIBOSIDES RODENTS Space life sciences SYNCHRONOUS CULTURES SYNTHESIS Time Factors URACILS VERTEBRATES X RADIATION X-Rays
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