Urinary steroid profile in threatened abortion
A study of the urinary steroid profile in early pregnancy has been undertaken in order to re-evaluate the usefulness of the urinary determinations of pregnanolone, pregnanediol, pregnanetriol, and total estrogens in cases of threatened abortion. This investigation incorporates an enzymatic hydrolysi...
Gespeichert in:
| Veröffentlicht in: | American journal of obstetrics and gynecology 1969-08, Vol.104 (7), p.964-972 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 972 |
|---|---|
| container_issue | 7 |
| container_start_page | 964 |
| container_title | American journal of obstetrics and gynecology |
| container_volume | 104 |
| creator | Acevedo, H.F. Vela, B.A. Campbell, E.A. Strickler, H.S. Gilmore, J. Moraca, J.I. Arras, B.J. |
| description | A study of the urinary steroid profile in early pregnancy has been undertaken in order to re-evaluate the usefulness of the urinary determinations of pregnanolone, pregnanediol, pregnanetriol, and total estrogens in cases of threatened abortion. This investigation incorporates an enzymatic hydrolysis with gas-liquid chromatographic analysis for the pregnane metabolites and an automated assay for total estrogens. The results obtained in 62 patients confirm the value of the urinary determinations of pregnanediol and pregnanolone. They also suggest that the prognosis is good in cases which present clinical symptoms of threatened abortion but have normal urinary excretion of pregnanediol and pregnanolone. When the “biochemical progestational activity,” as evaluated by the analysis of pregnanolone and pregnanediol remains normal, abortion does not occur in the first trimester. |
| doi_str_mv | 10.1016/0002-9378(69)90687-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_84095789</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0002937869906875</els_id><sourcerecordid>84095789</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-9b41f24d3f38f3010b0545ee336c81029d6f54844d567f4a46fcce074c50bd733</originalsourceid><addsrcrecordid>eNp9UE1LAzEUDKLUWv0HCnsSPWxNNt8XQYpfUPBiz2E3ecHIdrcmW8F_b9aWHj09Hm9m3swgdEnwnGAi7jDGVampVDdC32oslCz5EZoSrGUplFDHaHqAnKKzlD7HtdLVBE241EwxPEXzVQxdHX-KNEDsgys2sfehhSJ0xfARoR6gA1fUTR-H0Hfn6MTXbYKL_Zyh1dPj--KlXL49vy4elqWlXA6lbhjxFXPUU-UpJrjBnHEASoVVBFfaCc-zAea4kJ7VTHhrAUtmOW6cpHSGrne62c7XFtJg1iFZaNu6g36bTPauuVQ6A9kOaGOfUgRvNjGscyBDsBlrMmNoM3ZghDZ_NRmeaVd7_W2zBncg7XvJ9_vdHXLI7wDRJBugs-BCBDsY14f_H_wCmap1gQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>84095789</pqid></control><display><type>article</type><title>Urinary steroid profile in threatened abortion</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Acevedo, H.F. ; Vela, B.A. ; Campbell, E.A. ; Strickler, H.S. ; Gilmore, J. ; Moraca, J.I. ; Arras, B.J.</creator><creatorcontrib>Acevedo, H.F. ; Vela, B.A. ; Campbell, E.A. ; Strickler, H.S. ; Gilmore, J. ; Moraca, J.I. ; Arras, B.J.</creatorcontrib><description>A study of the urinary steroid profile in early pregnancy has been undertaken in order to re-evaluate the usefulness of the urinary determinations of pregnanolone, pregnanediol, pregnanetriol, and total estrogens in cases of threatened abortion. This investigation incorporates an enzymatic hydrolysis with gas-liquid chromatographic analysis for the pregnane metabolites and an automated assay for total estrogens. The results obtained in 62 patients confirm the value of the urinary determinations of pregnanediol and pregnanolone. They also suggest that the prognosis is good in cases which present clinical symptoms of threatened abortion but have normal urinary excretion of pregnanediol and pregnanolone. When the “biochemical progestational activity,” as evaluated by the analysis of pregnanolone and pregnanediol remains normal, abortion does not occur in the first trimester.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/0002-9378(69)90687-5</identifier><identifier>PMID: 5794840</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Abortion, Threatened - diagnosis ; Abortion, Threatened - urine ; Autoanalysis ; Chromatography, Gas ; Estrogens - urine ; Female ; Gestational Age ; Humans ; Pregnancy ; Pregnanediol - urine ; Pregnanes - urine ; Pregnanetriol - urine</subject><ispartof>American journal of obstetrics and gynecology, 1969-08, Vol.104 (7), p.964-972</ispartof><rights>1969</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-9b41f24d3f38f3010b0545ee336c81029d6f54844d567f4a46fcce074c50bd733</citedby><cites>FETCH-LOGICAL-c357t-9b41f24d3f38f3010b0545ee336c81029d6f54844d567f4a46fcce074c50bd733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0002937869906875$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5794840$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Acevedo, H.F.</creatorcontrib><creatorcontrib>Vela, B.A.</creatorcontrib><creatorcontrib>Campbell, E.A.</creatorcontrib><creatorcontrib>Strickler, H.S.</creatorcontrib><creatorcontrib>Gilmore, J.</creatorcontrib><creatorcontrib>Moraca, J.I.</creatorcontrib><creatorcontrib>Arras, B.J.</creatorcontrib><title>Urinary steroid profile in threatened abortion</title><title>American journal of obstetrics and gynecology</title><addtitle>Am J Obstet Gynecol</addtitle><description>A study of the urinary steroid profile in early pregnancy has been undertaken in order to re-evaluate the usefulness of the urinary determinations of pregnanolone, pregnanediol, pregnanetriol, and total estrogens in cases of threatened abortion. This investigation incorporates an enzymatic hydrolysis with gas-liquid chromatographic analysis for the pregnane metabolites and an automated assay for total estrogens. The results obtained in 62 patients confirm the value of the urinary determinations of pregnanediol and pregnanolone. They also suggest that the prognosis is good in cases which present clinical symptoms of threatened abortion but have normal urinary excretion of pregnanediol and pregnanolone. When the “biochemical progestational activity,” as evaluated by the analysis of pregnanolone and pregnanediol remains normal, abortion does not occur in the first trimester.</description><subject>Abortion, Threatened - diagnosis</subject><subject>Abortion, Threatened - urine</subject><subject>Autoanalysis</subject><subject>Chromatography, Gas</subject><subject>Estrogens - urine</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Pregnancy</subject><subject>Pregnanediol - urine</subject><subject>Pregnanes - urine</subject><subject>Pregnanetriol - urine</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1969</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UE1LAzEUDKLUWv0HCnsSPWxNNt8XQYpfUPBiz2E3ecHIdrcmW8F_b9aWHj09Hm9m3swgdEnwnGAi7jDGVampVDdC32oslCz5EZoSrGUplFDHaHqAnKKzlD7HtdLVBE241EwxPEXzVQxdHX-KNEDsgys2sfehhSJ0xfARoR6gA1fUTR-H0Hfn6MTXbYKL_Zyh1dPj--KlXL49vy4elqWlXA6lbhjxFXPUU-UpJrjBnHEASoVVBFfaCc-zAea4kJ7VTHhrAUtmOW6cpHSGrne62c7XFtJg1iFZaNu6g36bTPauuVQ6A9kOaGOfUgRvNjGscyBDsBlrMmNoM3ZghDZ_NRmeaVd7_W2zBncg7XvJ9_vdHXLI7wDRJBugs-BCBDsY14f_H_wCmap1gQ</recordid><startdate>19690801</startdate><enddate>19690801</enddate><creator>Acevedo, H.F.</creator><creator>Vela, B.A.</creator><creator>Campbell, E.A.</creator><creator>Strickler, H.S.</creator><creator>Gilmore, J.</creator><creator>Moraca, J.I.</creator><creator>Arras, B.J.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19690801</creationdate><title>Urinary steroid profile in threatened abortion</title><author>Acevedo, H.F. ; Vela, B.A. ; Campbell, E.A. ; Strickler, H.S. ; Gilmore, J. ; Moraca, J.I. ; Arras, B.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-9b41f24d3f38f3010b0545ee336c81029d6f54844d567f4a46fcce074c50bd733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1969</creationdate><topic>Abortion, Threatened - diagnosis</topic><topic>Abortion, Threatened - urine</topic><topic>Autoanalysis</topic><topic>Chromatography, Gas</topic><topic>Estrogens - urine</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>Pregnancy</topic><topic>Pregnanediol - urine</topic><topic>Pregnanes - urine</topic><topic>Pregnanetriol - urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Acevedo, H.F.</creatorcontrib><creatorcontrib>Vela, B.A.</creatorcontrib><creatorcontrib>Campbell, E.A.</creatorcontrib><creatorcontrib>Strickler, H.S.</creatorcontrib><creatorcontrib>Gilmore, J.</creatorcontrib><creatorcontrib>Moraca, J.I.</creatorcontrib><creatorcontrib>Arras, B.J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Acevedo, H.F.</au><au>Vela, B.A.</au><au>Campbell, E.A.</au><au>Strickler, H.S.</au><au>Gilmore, J.</au><au>Moraca, J.I.</au><au>Arras, B.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urinary steroid profile in threatened abortion</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1969-08-01</date><risdate>1969</risdate><volume>104</volume><issue>7</issue><spage>964</spage><epage>972</epage><pages>964-972</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><abstract>A study of the urinary steroid profile in early pregnancy has been undertaken in order to re-evaluate the usefulness of the urinary determinations of pregnanolone, pregnanediol, pregnanetriol, and total estrogens in cases of threatened abortion. This investigation incorporates an enzymatic hydrolysis with gas-liquid chromatographic analysis for the pregnane metabolites and an automated assay for total estrogens. The results obtained in 62 patients confirm the value of the urinary determinations of pregnanediol and pregnanolone. They also suggest that the prognosis is good in cases which present clinical symptoms of threatened abortion but have normal urinary excretion of pregnanediol and pregnanolone. When the “biochemical progestational activity,” as evaluated by the analysis of pregnanolone and pregnanediol remains normal, abortion does not occur in the first trimester.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>5794840</pmid><doi>10.1016/0002-9378(69)90687-5</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9378 |
| ispartof | American journal of obstetrics and gynecology, 1969-08, Vol.104 (7), p.964-972 |
| issn | 0002-9378 1097-6868 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84095789 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Abortion, Threatened - diagnosis Abortion, Threatened - urine Autoanalysis Chromatography, Gas Estrogens - urine Female Gestational Age Humans Pregnancy Pregnanediol - urine Pregnanes - urine Pregnanetriol - urine |
| title | Urinary steroid profile in threatened abortion |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T12%3A29%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Urinary%20steroid%20profile%20in%20threatened%20abortion&rft.jtitle=American%20journal%20of%20obstetrics%20and%20gynecology&rft.au=Acevedo,%20H.F.&rft.date=1969-08-01&rft.volume=104&rft.issue=7&rft.spage=964&rft.epage=972&rft.pages=964-972&rft.issn=0002-9378&rft.eissn=1097-6868&rft_id=info:doi/10.1016/0002-9378(69)90687-5&rft_dat=%3Cproquest_cross%3E84095789%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=84095789&rft_id=info:pmid/5794840&rft_els_id=0002937869906875&rfr_iscdi=true |