Studies on the adrenal cortex of hypophysectomized rats: a model for abnormal cellular atrophy and death

Biochemical and ultrastructural studies indicate that the atrophy of adrenal cortex in hypoyhysectomized rats involves the following changes: (1) One to two days after hypophysectomy, there is loss of "template activity" resulting from cumulative DNA-damage and heterochromatinization. In v...

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