THE ABSORPTION OF PHENFORMIN AND ITS EFFECTS ON GLUCOSE AND WATER ABSORPTION IN ISOLATED PERFUSED RAT SMALL INTESTINE

The effects of phenformin on glucose and water absorption from isolated perfused rat small intestine were studied. Luminal phenformin inhibited glucose and water absorption progressively as its concentration was increased from 0·1-1·0 mg.ml -1 . At 0·5 mg phenformin ml -1 , inhibition increased w...

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Veröffentlicht in:	Experimental physiology 1977-07, Vol.62 (3), p.247-255
Hauptverfasser:	Gardner, M. L. G., Langslow, D. R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dose-Response Relationship, Drug Female Glucose - metabolism In Vitro Techniques Intestine, Small - metabolism Perfusion Phenformin - metabolism Phenformin - pharmacology Rats Water - metabolism
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