A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity

METHIONINE and leucine enkephalin, the morphinomimetic pentapeptides from mammalian brain 1–3 produce a weak and short-lived analgesia following intracerebroventricular (i.c.v) or intravenous (i.v.) administration to mice 4 and rats 5 . β-endorphin 6,7 , another morphinomimetic fragment of β-lipotro...

Ausführliche Beschreibung