Efficacy of p16 and ProExC Immunostaining in the Detection of High-Grade Cervical Intraepithelial Neoplasia and Cervical Carcinoma

We compared the efficacy of p16 and ProExC immunostaining in detecting cervical intraepithelial neoplasia (CIN) 2+ in 136 formalin-fixed, paraffin-embedded cervical tissue specimens with consensus diagnoses of normal cervix, CIN 1, CIN 2, CIN 3, and carcinoma. Diffuse staining patterns of more than...

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Veröffentlicht in:	American journal of clinical pathology 2011-02, Vol.135 (2), p.212-220
Hauptverfasser:	MING GUO, BARUCH, Amy C, SILVA, Elvio G, YEE JEE JAN, LIN, E, SNEIGE, Nour, DEAVERS, Michael T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biological and medical sciences Biomarkers, Tumor - analysis Cervical Intraepithelial Neoplasia - pathology Cervix Uteri - pathology Cyclin-Dependent Kinase Inhibitor p16 - analysis DNA, Viral - analysis Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Infectious diseases Investigative techniques, diagnostic techniques (general aspects) Medical sciences Middle Aged Papillomaviridae - genetics Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Reagent Kits, Diagnostic Staining and Labeling Tumors Uterine Cervical Neoplasms - pathology Viral diseases
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