State of the Art in Topical Wound-Healing Products

Chronic wounds represent a significant medical burden. Such wounds fail to normally progress through the stages of healing, often complicated by a proinflammatory milieu caused by increased proteinases, hypoxia, and bacterial burden. As a result, several modalities, such as dressings, antimicrobials...

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Veröffentlicht in:Plastic and reconstructive surgery (1963) 2011-01, Vol.127 (Suppl 1), p.44S-59S
Hauptverfasser: Fan, Kenneth, Tang, Jennifer, Escandon, Julia, Kirsner, Robert S.
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container_end_page 59S
container_issue Suppl 1
container_start_page 44S
container_title Plastic and reconstructive surgery (1963)
container_volume 127
creator Fan, Kenneth
Tang, Jennifer
Escandon, Julia
Kirsner, Robert S.
description Chronic wounds represent a significant medical burden. Such wounds fail to normally progress through the stages of healing, often complicated by a proinflammatory milieu caused by increased proteinases, hypoxia, and bacterial burden. As a result, several modalities, such as dressings, antimicrobials, growth factors, and human skin substitutes, have been devised in an attempt to correct the chronic wound environment. This review addresses these modalities with a focus on evidence and randomized controlled trials.
doi_str_mv 10.1097/PRS.0b013e3181fbe275
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subjects Administration, Topical
Anti-Infective Agents - administration & dosage
Bandages
Chronic Disease
Humans
Intercellular Signaling Peptides and Proteins - administration & dosage
Randomized Controlled Trials as Topic
Skin Transplantation
Skin, Artificial
Tissue Engineering
Wound Healing - drug effects
Wound Healing - physiology
Wounds and Injuries - physiopathology
Wounds and Injuries - therapy
title State of the Art in Topical Wound-Healing Products
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