Studies of thyroxin secretion and degradation rate in children with different thyroidal functional states. Comparison of thyroid function in children and adults
Fractional turnover rate, degradation rate, and other parameters of thyroxin metabolism and the secretion rate of organic iodine were studied in a number of euthyroid normal children, euthyroid obese children, and children with altered thyroid function. The results give further evidence of a higher...
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Veröffentlicht in: | The Journal of pediatrics 1965-09, Vol.67 (3), p.343-352 |
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container_title | The Journal of pediatrics |
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creator | Croughs, W. Visser, H.K.A. Woldring, M.G. |
description | Fractional turnover rate, degradation rate, and other parameters of thyroxin metabolism and the secretion rate of organic iodine were studied in a number of euthyroid normal children, euthyroid obese children, and children with altered thyroid function. The results give further evidence of a higher metabolism of thyroxin in children as compared with adults. In obese children, a significantly lower fractional turnover rate of thyroxin was found; this may indicate lower peripheral demands for thyroxin and lower tissue metabolism in these children. |
doi_str_mv | 10.1016/S0022-3476(65)80394-8 |
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In obese children, a significantly lower fractional turnover rate of thyroxin was found; this may indicate lower peripheral demands for thyroxin and lower tissue metabolism in these children.</description><subject>Adolescent</subject><subject>Aging</subject><subject>Body Weight</subject><subject>Child</subject><subject>Goiter</subject><subject>Humans</subject><subject>Hypopituitarism</subject><subject>Hypothyroidism</subject><subject>Infant</subject><subject>Iodine Isotopes</subject><subject>Metabolism</subject><subject>Obesity</subject><subject>Old Medline</subject><subject>Thyroid Function Tests</subject><subject>Thyroxine</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1965</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1uFDEQhC1ERDaBRyDyKSKHSdrjWXt8itAqP0iRcgicLY_dZo1mZza2J5C34VHx_hCUE6fulr6qkl2EfGRwzoCJiweAuq54I8UnMT9rgaumat-QGQMlK9Fy_pbMXpBDcpTSDwBQDcA7csga3jAp-Yz8fsiTC5jo6GlePsfxVxhoQhsxh3GgZnDU4fdonNne0WSkhbDL0LuIA_0Z8pK64D2WK-8sgjM99dNgN5KyplxU6ZwuxtXaxJCKz9-04F7AV7abXOOmPqf35MCbPuGH_Twm366vvi5uq7v7my-Lz3eV5YLnyjKhrGWdsKIxnfJoO9YZkNwD852tBYBTrZdK2RrmqFA00jnpTauM6XjHj8npzncdx8cJU9arkCz2vRlwnJJuG6hBtqKA8x1o45hSRK_XMaxMfNYM9KYava1Gb_5di7neVqPbojvZB0zdCt0_1b6LAlzuACzPfAoYdbIBB4suRLRZuzH8J-IP4Fajew</recordid><startdate>196509</startdate><enddate>196509</enddate><creator>Croughs, W.</creator><creator>Visser, H.K.A.</creator><creator>Woldring, M.G.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196509</creationdate><title>Studies of thyroxin secretion and degradation rate in children with different thyroidal functional states. 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In obese children, a significantly lower fractional turnover rate of thyroxin was found; this may indicate lower peripheral demands for thyroxin and lower tissue metabolism in these children.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>14341773</pmid><doi>10.1016/S0022-3476(65)80394-8</doi><tpages>10</tpages></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Adolescent Aging Body Weight Child Goiter Humans Hypopituitarism Hypothyroidism Infant Iodine Isotopes Metabolism Obesity Old Medline Thyroid Function Tests Thyroxine |
title | Studies of thyroxin secretion and degradation rate in children with different thyroidal functional states. Comparison of thyroid function in children and adults |
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