5-Hydroxytryptamine and punishment
PUNISHMENT is defined as the presentation of a noxious stimulus and results in the suppression of behaviour. This suppressive effect of punishment is seen clearly in conflict situations where the organism is encouraged to respond and then is punished for doing so. Brain 5-hydroxytryptamine (5-HT) sy...
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| Veröffentlicht in: | Nature (London) 1977-08, Vol.268 (5622), p.741-743 |
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| container_issue | 5622 |
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| container_title | Nature (London) |
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| creator | TYE, N. C EVERITT, B. J IVERSEN, SUSAN D |
| description | PUNISHMENT is defined as the presentation of a noxious stimulus and results in the suppression of behaviour. This suppressive effect of punishment is seen clearly in conflict situations where the organism is encouraged to respond and then is punished for doing so. Brain 5-hydroxytryptamine (5-HT) systems have been implicated in the processes associated with the response to punishment. We show here that selective neurotoxin lesions to the 5-HT forebrain pathways reverse the suppressive effects of punishment, as do minor tranquillisers, supporting the view that 5-HT has a central role in conflict behaviour and in the effect of minor tranquillisers on such behaviour. |
| doi_str_mv | 10.1038/268741a0 |
| format | Article |
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| ispartof | Nature (London), 1977-08, Vol.268 (5622), p.741-743 |
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| source | MEDLINE; Nature Journals Online; SpringerLink Journals - AutoHoldings |
| subjects | Animals Brain - drug effects Cerebral Cortex - metabolism Humanities and Social Sciences Hypothalamus - metabolism letter Male multidisciplinary Norepinephrine - metabolism Punishment - drug effects Punishment - physiology Rats Science Science (multidisciplinary) Serotonin - analogs & derivatives Serotonin - pharmacology Serotonin - physiology |
| title | 5-Hydroxytryptamine and punishment |
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