New Genetic Marker in Human Parotid Saliva (Pm)
In 195 parotid saliva samples collected at random from a Japanese population, two phenotypes were observed by electrophoresis in acid-urea starch gels. The protein showing polymorphisms was detected in the middle zone between Pa and Pb, and was tentatively designated Pm. Inheritance was controlled b...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1977-07, Vol.197 (4301), p.378-379 |
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| container_issue | 4301 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Ikemoto, Shigenori Minaguchi, Kiyoshi Suzuki, Kazuo Tomita, Koichi |
| description | In 195 parotid saliva samples collected at random from a Japanese population, two phenotypes were observed by electrophoresis in acid-urea starch gels. The protein showing polymorphisms was detected in the middle zone between Pa and Pb, and was tentatively designated Pm. Inheritance was controlled by a dominant allele at an autosomal locus. The frequencies of the genes determining these phenotypes were, for the Japanese population studied, Pm$^{+}$ =.38 ± .03, Pm$^{-}$ =.62 ± .03. |
| doi_str_mv | 10.1126/science.877561 |
| format | Article |
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The protein showing polymorphisms was detected in the middle zone between Pa and Pb, and was tentatively designated Pm. Inheritance was controlled by a dominant allele at an autosomal locus. The frequencies of the genes determining these phenotypes were, for the Japanese population studied, Pm$^{+}$ =.38 ± .03, Pm$^{-}$ =.62 ± .03.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.877561</identifier><identifier>PMID: 877561</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Asian Continental Ancestry Group ; China - ethnology ; Chronic diseases ; Demyelinating diseases ; Electrophoresis ; Gels ; Gene Frequency ; Humans ; Japan - ethnology ; Nervous system diseases ; Phenotype ; Phenotypes ; Polymorphism, Genetic ; Proteins - analysis ; Relapse ; Saliva ; Saliva - analysis ; Viral diseases ; Viruses</subject><ispartof>Science (American Association for the Advancement of Science), 1977-07, Vol.197 (4301), p.378-379</ispartof><rights>Copyright 1977 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c340t-633337d75a747098be46ea50cb9f2f2d54f4da891a1511cb0bffdaac6f8c37a63</citedby><cites>FETCH-LOGICAL-c340t-633337d75a747098be46ea50cb9f2f2d54f4da891a1511cb0bffdaac6f8c37a63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1744347$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1744347$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2884,2885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/877561$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ikemoto, Shigenori</creatorcontrib><creatorcontrib>Minaguchi, Kiyoshi</creatorcontrib><creatorcontrib>Suzuki, Kazuo</creatorcontrib><creatorcontrib>Tomita, Koichi</creatorcontrib><title>New Genetic Marker in Human Parotid Saliva (Pm)</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>In 195 parotid saliva samples collected at random from a Japanese population, two phenotypes were observed by electrophoresis in acid-urea starch gels. The protein showing polymorphisms was detected in the middle zone between Pa and Pb, and was tentatively designated Pm. Inheritance was controlled by a dominant allele at an autosomal locus. The frequencies of the genes determining these phenotypes were, for the Japanese population studied, Pm$^{+}$ =.38 ± .03, Pm$^{-}$ =.62 ± .03.</description><subject>Asian Continental Ancestry Group</subject><subject>China - ethnology</subject><subject>Chronic diseases</subject><subject>Demyelinating diseases</subject><subject>Electrophoresis</subject><subject>Gels</subject><subject>Gene Frequency</subject><subject>Humans</subject><subject>Japan - ethnology</subject><subject>Nervous system diseases</subject><subject>Phenotype</subject><subject>Phenotypes</subject><subject>Polymorphism, Genetic</subject><subject>Proteins - analysis</subject><subject>Relapse</subject><subject>Saliva</subject><subject>Saliva - analysis</subject><subject>Viral diseases</subject><subject>Viruses</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkD1PwzAQhi3EVymsTAyZEAxJ7diJ7RFV0CIVqATM1sWxJZd8FDsB8e8JSgUSt9zwPvdI9yJ0TnBCSJrPgnam0SYRnGc52UMTgmUWyxTTfTTBmOaxwDw7RichbDAeMkmP0OFIT9Ds0XxGC9OYzunoAfyb8ZFromVfQxOtwbedK6NnqNwHRFfr-voUHViogjnb7Sl6vbt9mS_j1dPifn6zijVluItzOgwveQaccSxFYVhuIMO6kDa1aZkxy0oQkgDJCNEFLqwtAXRuhaYccjpFl6N369v33oRO1S5oU1XQmLYPSlApBRNiAJMR1L4NwRurtt7V4L8UweqnILUrSI0vDwcXO3Nf1Kb8xf_Hm9C1_k_GGaOM028rxmoa</recordid><startdate>19770722</startdate><enddate>19770722</enddate><creator>Ikemoto, Shigenori</creator><creator>Minaguchi, Kiyoshi</creator><creator>Suzuki, Kazuo</creator><creator>Tomita, Koichi</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19770722</creationdate><title>New Genetic Marker in Human Parotid Saliva (Pm)</title><author>Ikemoto, Shigenori ; Minaguchi, Kiyoshi ; Suzuki, Kazuo ; Tomita, Koichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c340t-633337d75a747098be46ea50cb9f2f2d54f4da891a1511cb0bffdaac6f8c37a63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Asian Continental Ancestry Group</topic><topic>China - ethnology</topic><topic>Chronic diseases</topic><topic>Demyelinating diseases</topic><topic>Electrophoresis</topic><topic>Gels</topic><topic>Gene Frequency</topic><topic>Humans</topic><topic>Japan - ethnology</topic><topic>Nervous system diseases</topic><topic>Phenotype</topic><topic>Phenotypes</topic><topic>Polymorphism, Genetic</topic><topic>Proteins - analysis</topic><topic>Relapse</topic><topic>Saliva</topic><topic>Saliva - analysis</topic><topic>Viral diseases</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ikemoto, Shigenori</creatorcontrib><creatorcontrib>Minaguchi, Kiyoshi</creatorcontrib><creatorcontrib>Suzuki, Kazuo</creatorcontrib><creatorcontrib>Tomita, Koichi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ikemoto, Shigenori</au><au>Minaguchi, Kiyoshi</au><au>Suzuki, Kazuo</au><au>Tomita, Koichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New Genetic Marker in Human Parotid Saliva (Pm)</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1977-07-22</date><risdate>1977</risdate><volume>197</volume><issue>4301</issue><spage>378</spage><epage>379</epage><pages>378-379</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>In 195 parotid saliva samples collected at random from a Japanese population, two phenotypes were observed by electrophoresis in acid-urea starch gels. 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| fulltext | fulltext |
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| ispartof | Science (American Association for the Advancement of Science), 1977-07, Vol.197 (4301), p.378-379 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83998488 |
| source | MEDLINE; Science Magazine; JSTOR Archive Collection A-Z Listing |
| subjects | Asian Continental Ancestry Group China - ethnology Chronic diseases Demyelinating diseases Electrophoresis Gels Gene Frequency Humans Japan - ethnology Nervous system diseases Phenotype Phenotypes Polymorphism, Genetic Proteins - analysis Relapse Saliva Saliva - analysis Viral diseases Viruses |
| title | New Genetic Marker in Human Parotid Saliva (Pm) |
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