Vogt-Koyanagi-Harada Syndrome
We studied 51 patients who developed Vogt-Koyanagi-Harada (V-K-H) syndrome after corticosteroid therapy. The final visual acuity was better than 6/15 (20/50) in 50%, and less than 6/60 (20/200) in 25% of the patients. The severity and extraocular manifestations of this disease also appeared to be le...
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Veröffentlicht in: | American journal of ophthalmology 1977-05, Vol.83 (5), p.735-740 |
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creator | Ohno, Shigeaki Char, Devron H. Kimura, Samuel J. Richard O'Connor, G. |
description | We studied 51 patients who developed Vogt-Koyanagi-Harada (V-K-H) syndrome after corticosteroid therapy. The final visual acuity was better than 6/15 (20/50) in 50%, and less than 6/60 (20/200) in 25% of the patients. The severity and extraocular manifestations of this disease also appeared to be less than observed in patients before the clinical use of corticosteroids. Corticosteroid therapy probably altered the clinical picture in this disease, although other possibilities, including a skewed patient population, may account for these differences. |
doi_str_mv | 10.1016/0002-9394(77)90142-8 |
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The final visual acuity was better than 6/15 (20/50) in 50%, and less than 6/60 (20/200) in 25% of the patients. The severity and extraocular manifestations of this disease also appeared to be less than observed in patients before the clinical use of corticosteroids. Corticosteroid therapy probably altered the clinical picture in this disease, although other possibilities, including a skewed patient population, may account for these differences.</description><identifier>ISSN: 0002-9394</identifier><identifier>EISSN: 1879-1891</identifier><identifier>DOI: 10.1016/0002-9394(77)90142-8</identifier><identifier>PMID: 868972</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adrenal Cortex Hormones - therapeutic use ; Adult ; Central Nervous System Diseases - etiology ; Child ; Female ; Humans ; Male ; Middle Aged ; Pigmentation Disorders - diagnosis ; Pigmentation Disorders - drug therapy ; Uveitis - diagnosis ; Uveitis - drug therapy ; Uveomeningoencephalitic Syndrome - diagnosis ; Uveomeningoencephalitic Syndrome - drug therapy ; Visual Acuity</subject><ispartof>American journal of ophthalmology, 1977-05, Vol.83 (5), p.735-740</ispartof><rights>1977 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-6bc5df9c78b74dc2792b9dbd2368806c92976d2449134ff37010c59b7ad6d0243</citedby><cites>FETCH-LOGICAL-c356t-6bc5df9c78b74dc2792b9dbd2368806c92976d2449134ff37010c59b7ad6d0243</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0002939477901428$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/868972$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ohno, Shigeaki</creatorcontrib><creatorcontrib>Char, Devron H.</creatorcontrib><creatorcontrib>Kimura, Samuel J.</creatorcontrib><creatorcontrib>Richard O'Connor, G.</creatorcontrib><title>Vogt-Koyanagi-Harada Syndrome</title><title>American journal of ophthalmology</title><addtitle>Am J Ophthalmol</addtitle><description>We studied 51 patients who developed Vogt-Koyanagi-Harada (V-K-H) syndrome after corticosteroid therapy. The final visual acuity was better than 6/15 (20/50) in 50%, and less than 6/60 (20/200) in 25% of the patients. The severity and extraocular manifestations of this disease also appeared to be less than observed in patients before the clinical use of corticosteroids. Corticosteroid therapy probably altered the clinical picture in this disease, although other possibilities, including a skewed patient population, may account for these differences.</description><subject>Adolescent</subject><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Adult</subject><subject>Central Nervous System Diseases - etiology</subject><subject>Child</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pigmentation Disorders - diagnosis</subject><subject>Pigmentation Disorders - drug therapy</subject><subject>Uveitis - diagnosis</subject><subject>Uveitis - drug therapy</subject><subject>Uveomeningoencephalitic Syndrome - diagnosis</subject><subject>Uveomeningoencephalitic Syndrome - drug therapy</subject><subject>Visual Acuity</subject><issn>0002-9394</issn><issn>1879-1891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLAzEUhYP4qtV_UMGV6CKaV5PcjSBFrVhw4WMbMkmmjHQmNZkK_fdOndKlq8vlfOfAOQiNKLmhhMpbQgjDwEFcKXUNhAqG9R4aUK0AUw10Hw12yDE6yfmre6US6ggdaqlBsQE6_4zzFr_EtW3svMJTm6y3F2_rxqdYh1N0UNpFDmfbO0Qfjw_vkymevT49T-5n2PGxbLEs3NiX4JQulPCOKWAF-MIzLrUm0gEDJT0TAigXZckVocSNoVDWS0-Y4EN02ecuU_xehdyausouLBa2CXGVjeagmQbWgaIHXYo5p1CaZapqm9aGErMZxWwam01jo5T5G6VzD9Fom78q6uB3pn6FTr7r5dB1_KlCMtlVoXHBVym41vhY_Z__C_lkbhg</recordid><startdate>197705</startdate><enddate>197705</enddate><creator>Ohno, Shigeaki</creator><creator>Char, Devron H.</creator><creator>Kimura, Samuel J.</creator><creator>Richard O'Connor, G.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197705</creationdate><title>Vogt-Koyanagi-Harada Syndrome</title><author>Ohno, Shigeaki ; Char, Devron H. ; Kimura, Samuel J. ; Richard O'Connor, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-6bc5df9c78b74dc2792b9dbd2368806c92976d2449134ff37010c59b7ad6d0243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Adolescent</topic><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Adult</topic><topic>Central Nervous System Diseases - etiology</topic><topic>Child</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pigmentation Disorders - diagnosis</topic><topic>Pigmentation Disorders - drug therapy</topic><topic>Uveitis - diagnosis</topic><topic>Uveitis - drug therapy</topic><topic>Uveomeningoencephalitic Syndrome - diagnosis</topic><topic>Uveomeningoencephalitic Syndrome - drug therapy</topic><topic>Visual Acuity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ohno, Shigeaki</creatorcontrib><creatorcontrib>Char, Devron H.</creatorcontrib><creatorcontrib>Kimura, Samuel J.</creatorcontrib><creatorcontrib>Richard O'Connor, G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ohno, Shigeaki</au><au>Char, Devron H.</au><au>Kimura, Samuel J.</au><au>Richard O'Connor, G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vogt-Koyanagi-Harada Syndrome</atitle><jtitle>American journal of ophthalmology</jtitle><addtitle>Am J Ophthalmol</addtitle><date>1977-05</date><risdate>1977</risdate><volume>83</volume><issue>5</issue><spage>735</spage><epage>740</epage><pages>735-740</pages><issn>0002-9394</issn><eissn>1879-1891</eissn><abstract>We studied 51 patients who developed Vogt-Koyanagi-Harada (V-K-H) syndrome after corticosteroid therapy. The final visual acuity was better than 6/15 (20/50) in 50%, and less than 6/60 (20/200) in 25% of the patients. The severity and extraocular manifestations of this disease also appeared to be less than observed in patients before the clinical use of corticosteroids. Corticosteroid therapy probably altered the clinical picture in this disease, although other possibilities, including a skewed patient population, may account for these differences.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>868972</pmid><doi>10.1016/0002-9394(77)90142-8</doi><tpages>6</tpages></addata></record> |
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subjects | Adolescent Adrenal Cortex Hormones - therapeutic use Adult Central Nervous System Diseases - etiology Child Female Humans Male Middle Aged Pigmentation Disorders - diagnosis Pigmentation Disorders - drug therapy Uveitis - diagnosis Uveitis - drug therapy Uveomeningoencephalitic Syndrome - diagnosis Uveomeningoencephalitic Syndrome - drug therapy Visual Acuity |
title | Vogt-Koyanagi-Harada Syndrome |
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