Pharmacokinetics and metabolism of vinblastine in humans

The pharmacokinetics of vinblastine in humans was examined using a radioimmunoassay specific for both the Vinca alkaloids and aromatic ring [3H]vinblastine. The data were consistent with a three-compartment open model system with the following values, alpha phase: t1/2=3.90+/-1.46 min; Vc=16.8+/-7.1...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1977-08, Vol.37 (8 Pt 1), p.2597-2602
Hauptverfasser:	Owellen, R J, Hartke, C A, Hains, F O
Format:	Artikel
Sprache:	eng
Schlagworte:	Feces - analysis Humans Kinetics Radioimmunoassay Vinblastine - blood Vinblastine - metabolism Vinblastine - urine
Online-Zugang:	Volltext
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