Effect of Thyro-Parathyroidectomy and Adrenalectomy on Food Intake In Rats.
Summary A study is reported concerning the alteration in voluntary food intake of adult female Sprague-Dawley-Rolfsmeyer rats following thyro-parathyroidectomy and adre-nalectomy separately and together. Food consumption declined gradually to 24% at about 60 days following thyroidectomy. After 119 d...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1965-01, Vol.118 (1), p.25-27 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 118 |
| creator | Grossie, J. Turner, C. W. |
| description | Summary
A study is reported concerning the alteration in voluntary food intake of adult female Sprague-Dawley-Rolfsmeyer rats following thyro-parathyroidectomy and adre-nalectomy separately and together. Food consumption declined gradually to 24% at about 60 days following thyroidectomy. After 119 days, graded replacement therapy with thy-roxine was initiated. Levels of 0.5, 1.0, and 2.0 μg/100 g body weight failed to stimulate food intake comparable to the control level. Even on 2.0μg thyroxine after 189 days, food intake was still 31% below normal. After adrenalectomy, food intake was quickly reduced 27%, and after the thyroids were removed, food intake was reduced a total of 30%. |
| doi_str_mv | 10.3181/00379727-118-29745 |
| format | Article |
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A study is reported concerning the alteration in voluntary food intake of adult female Sprague-Dawley-Rolfsmeyer rats following thyro-parathyroidectomy and adre-nalectomy separately and together. Food consumption declined gradually to 24% at about 60 days following thyroidectomy. After 119 days, graded replacement therapy with thy-roxine was initiated. Levels of 0.5, 1.0, and 2.0 μg/100 g body weight failed to stimulate food intake comparable to the control level. Even on 2.0μg thyroxine after 189 days, food intake was still 31% below normal. After adrenalectomy, food intake was quickly reduced 27%, and after the thyroids were removed, food intake was reduced a total of 30%.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-118-29745</identifier><identifier>PMID: 14254563</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adrenalectomy ; Appetite ; Behavior, Animal ; Eating ; Hypoparathyroidism ; Old Medline ; Parathyroidectomy ; Pharmacology ; Physiology ; Rats ; Thyroidectomy ; Thyroxine</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1965-01, Vol.118 (1), p.25-27</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c256t-4741692605d4eb8a84ea5c0aa4f5d589a42e7489dc9524c43b13e633bbb17dcc3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14254563$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grossie, J.</creatorcontrib><creatorcontrib>Turner, C. W.</creatorcontrib><title>Effect of Thyro-Parathyroidectomy and Adrenalectomy on Food Intake In Rats.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
A study is reported concerning the alteration in voluntary food intake of adult female Sprague-Dawley-Rolfsmeyer rats following thyro-parathyroidectomy and adre-nalectomy separately and together. Food consumption declined gradually to 24% at about 60 days following thyroidectomy. After 119 days, graded replacement therapy with thy-roxine was initiated. Levels of 0.5, 1.0, and 2.0 μg/100 g body weight failed to stimulate food intake comparable to the control level. Even on 2.0μg thyroxine after 189 days, food intake was still 31% below normal. After adrenalectomy, food intake was quickly reduced 27%, and after the thyroids were removed, food intake was reduced a total of 30%.</description><subject>Adrenalectomy</subject><subject>Appetite</subject><subject>Behavior, Animal</subject><subject>Eating</subject><subject>Hypoparathyroidism</subject><subject>Old Medline</subject><subject>Parathyroidectomy</subject><subject>Pharmacology</subject><subject>Physiology</subject><subject>Rats</subject><subject>Thyroidectomy</subject><subject>Thyroxine</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1965</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAURS0EoqXwBxhQJja3_ozjsapaqKgEQmW2HNuBliQudjL035PQIDam-_R07h0OALcYTSnO8AwhKqQgAmKcQSIF42dgjDnlkKZSnoNxD8CeGIGrGPcIYS5IeglGmBHOeErH4GlZFM40iS-S7ccxePiig276a2e7v6-Oia5tMrfB1bocPr5OVt7bZF03-tN1kbzqJk6vwUWhy-huhpyAt9Vyu3iEm-eH9WK-gYbwtIFMMJxKkiJumcsznTGnuUFas4JbnknNiBMsk9ZITphhNMfUpZTmeY6FNYZOwP1p9xD8V-tio6pdNK4sde18G1VGZSoQJR1ITqAJPsbgCnUIu0qHo8JI9QrVr0LVKVQ_CrvS3bDe5pWzf5XBWQfMTkDU707tfRs6M_G_yW_zD3jh</recordid><startdate>196501</startdate><enddate>196501</enddate><creator>Grossie, J.</creator><creator>Turner, C. W.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196501</creationdate><title>Effect of Thyro-Parathyroidectomy and Adrenalectomy on Food Intake In Rats.</title><author>Grossie, J. ; Turner, C. W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c256t-4741692605d4eb8a84ea5c0aa4f5d589a42e7489dc9524c43b13e633bbb17dcc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1965</creationdate><topic>Adrenalectomy</topic><topic>Appetite</topic><topic>Behavior, Animal</topic><topic>Eating</topic><topic>Hypoparathyroidism</topic><topic>Old Medline</topic><topic>Parathyroidectomy</topic><topic>Pharmacology</topic><topic>Physiology</topic><topic>Rats</topic><topic>Thyroidectomy</topic><topic>Thyroxine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grossie, J.</creatorcontrib><creatorcontrib>Turner, C. W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grossie, J.</au><au>Turner, C. W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Thyro-Parathyroidectomy and Adrenalectomy on Food Intake In Rats.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1965-01</date><risdate>1965</risdate><volume>118</volume><issue>1</issue><spage>25</spage><epage>27</epage><pages>25-27</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
A study is reported concerning the alteration in voluntary food intake of adult female Sprague-Dawley-Rolfsmeyer rats following thyro-parathyroidectomy and adre-nalectomy separately and together. Food consumption declined gradually to 24% at about 60 days following thyroidectomy. After 119 days, graded replacement therapy with thy-roxine was initiated. Levels of 0.5, 1.0, and 2.0 μg/100 g body weight failed to stimulate food intake comparable to the control level. Even on 2.0μg thyroxine after 189 days, food intake was still 31% below normal. After adrenalectomy, food intake was quickly reduced 27%, and after the thyroids were removed, food intake was reduced a total of 30%.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14254563</pmid><doi>10.3181/00379727-118-29745</doi><tpages>3</tpages></addata></record> |
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| ispartof | Experimental biology and medicine (Maywood, N.J.), 1965-01, Vol.118 (1), p.25-27 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adrenalectomy Appetite Behavior, Animal Eating Hypoparathyroidism Old Medline Parathyroidectomy Pharmacology Physiology Rats Thyroidectomy Thyroxine |
| title | Effect of Thyro-Parathyroidectomy and Adrenalectomy on Food Intake In Rats. |
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