Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase

Methoxypolyethylene glycols of 1900 daltons (PEG-1900) or 5000 daltons (PEG-5000) were covalently attached to bovine liver catalase using 2,4,6-trichloro-s-triazine as the coupling agent. Rabbits were immunized by the intravenous and intramuscular routes with catalase modified by covalent attachment...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 1977-06, Vol.252 (11), p.3582-3586
Hauptverfasser:	Abuchowski, A, McCoy, J R, Palczuk, N C, van Es, T, Davis, F F
Format:	Artikel
Sprache:	eng
Schlagworte:	Acatalasia Animals Antibody Formation - drug effects Catalase - blood Catalase - immunology Cattle Complement Fixation Tests Hot Temperature Hydrogen-Ion Concentration Immunodiffusion Liver Mice Molecular Weight Peptide Hydrolases Polyethylene Glycols - pharmacology Rabbits
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!