Globin biosynthesis in sickle cell, Hb SC, and Hb C diseases

The wide range of globin synthesis ratios reported in patients with sickle cell disease casts doubt on whether the presence of genes for α- or β-thalassemia in combination with Hb S can be detected by globin synthesis studies. We have studied globin synthesis in 20 patients with Hb SS who had a mean...

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Veröffentlicht in:	The Journal of pediatrics 1977-07, Vol.91 (1), p.13-18
Hauptverfasser:	Kim, Haewon C., Weierbach, Robert G., Friedman, Shlomo, Schwartz, Elias
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anemia, Sickle Cell - diagnosis Anemia, Sickle Cell - metabolism Child Child, Preschool Female Globins - biosynthesis Hemoglobin C - biosynthesis Hemoglobin C Disease - diagnosis Hemoglobin C Disease - metabolism Hemoglobin, Sickle - biosynthesis Homozygote Humans Infant Male Thalassemia - metabolism
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