Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction
Technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigrams were obtained in 68 patients during acute myocardial infarction (AMI) and at follow-up 15.9 +/- 8.8 weeks later. All patients with AMI had a positive scintigram (2+ or greater); only one of 46 control patients (2%) had a positi...
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| Veröffentlicht in: | Circulation (New York, N.Y.) N.Y.), 1977-08, Vol.56 (2), p.181-187 |
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| container_title | Circulation (New York, N.Y.) |
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| creator | Olson, H G Lyons, K P Aronow, W S Brown, W T Greenfield, R S |
| description | Technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigrams were obtained in 68 patients during acute myocardial infarction (AMI) and at follow-up 15.9 +/- 8.8 weeks later. All patients with AMI had a positive scintigram (2+ or greater); only one of 46 control patients (2%) had a positive (2+) scintigram. At follow-up scintigraphy 6 to 37 weeks following AMI, 57% of patients had a persistently positive scintigram even though recurrent AMI was suspected in only one of these patients. Patients with persistently positive scintigrams tended to have more severe disease as evidenced by compensated congested heart failure (41%) persistent angina (77%), and ECG evidence of ventricular dyssynergy (51%), We conclude that 1) in patients with prior AMI, a 2+ abnormality on 99mTc-PYP scintigram may not represent new AMI; 2) a persistently positive 99mTc- PYP scintigram may have prognostic implications since it occurs predominantly in patients with severe symptomatic coronary disease. |
| doi_str_mv | 10.1161/01.CIR.56.2.181 |
| format | Article |
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All patients with AMI had a positive scintigram (2+ or greater); only one of 46 control patients (2%) had a positive (2+) scintigram. At follow-up scintigraphy 6 to 37 weeks following AMI, 57% of patients had a persistently positive scintigram even though recurrent AMI was suspected in only one of these patients. Patients with persistently positive scintigrams tended to have more severe disease as evidenced by compensated congested heart failure (41%) persistent angina (77%), and ECG evidence of ventricular dyssynergy (51%), We conclude that 1) in patients with prior AMI, a 2+ abnormality on 99mTc-PYP scintigram may not represent new AMI; 2) a persistently positive 99mTc- PYP scintigram may have prognostic implications since it occurs predominantly in patients with severe symptomatic coronary disease.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/01.CIR.56.2.181</identifier><identifier>PMID: 872308</identifier><language>eng</language><publisher>United States</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; Acute Disease ; Adult ; Aged ; BETA DECAY RADIOISOTOPES ; BETA-MINUS DECAY RADIOISOTOPES ; BODY ; CARDIOVASCULAR DISEASES ; CARDIOVASCULAR SYSTEM ; COUNTING TECHNIQUES ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DISEASES ; Female ; HEART ; HOURS LIVING RADIOISOTOPES ; Humans ; INTERMEDIATE MASS NUCLEI ; ISOMERIC NUCLEI ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; Male ; Middle Aged ; MUSCLES ; MYOCARDIAL INFARCTION ; Myocardial Infarction - diagnosis ; MYOCARDIUM ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANS ; OXYGEN COMPOUNDS ; PATIENTS ; PHOSPHORUS COMPOUNDS ; PYROPHOSPHATES ; RADIOISOTOPE SCANNING ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide Imaging ; SCINTISCANNING ; Technetium ; TECHNETIUM 99 ; TECHNETIUM ISOTOPES ; YEARS LIVING RADIOISOTOPES</subject><ispartof>Circulation (New York, N.Y.), 1977-08, Vol.56 (2), p.181-187</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c399t-cbb6b5fb1ae80860197c9c69cea754e266fa9363e40dc4d2061d914d0d0bb21b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,881,3674,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/872308$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/7323960$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Olson, H G</creatorcontrib><creatorcontrib>Lyons, K P</creatorcontrib><creatorcontrib>Aronow, W S</creatorcontrib><creatorcontrib>Brown, W T</creatorcontrib><creatorcontrib>Greenfield, R S</creatorcontrib><creatorcontrib>Univ. of California, Irvine</creatorcontrib><title>Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction</title><title>Circulation (New York, N.Y.)</title><addtitle>Circulation</addtitle><description>Technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigrams were obtained in 68 patients during acute myocardial infarction (AMI) and at follow-up 15.9 +/- 8.8 weeks later. All patients with AMI had a positive scintigram (2+ or greater); only one of 46 control patients (2%) had a positive (2+) scintigram. At follow-up scintigraphy 6 to 37 weeks following AMI, 57% of patients had a persistently positive scintigram even though recurrent AMI was suspected in only one of these patients. Patients with persistently positive scintigrams tended to have more severe disease as evidenced by compensated congested heart failure (41%) persistent angina (77%), and ECG evidence of ventricular dyssynergy (51%), We conclude that 1) in patients with prior AMI, a 2+ abnormality on 99mTc-PYP scintigram may not represent new AMI; 2) a persistently positive 99mTc- PYP scintigram may have prognostic implications since it occurs predominantly in patients with severe symptomatic coronary disease.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>Acute Disease</subject><subject>Adult</subject><subject>Aged</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BETA-MINUS DECAY RADIOISOTOPES</subject><subject>BODY</subject><subject>CARDIOVASCULAR DISEASES</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>COUNTING TECHNIQUES</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DISEASES</subject><subject>Female</subject><subject>HEART</subject><subject>HOURS LIVING RADIOISOTOPES</subject><subject>Humans</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>ISOMERIC NUCLEI</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>Male</subject><subject>Middle Aged</subject><subject>MUSCLES</subject><subject>MYOCARDIAL INFARCTION</subject><subject>Myocardial Infarction - diagnosis</subject><subject>MYOCARDIUM</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANS</subject><subject>OXYGEN COMPOUNDS</subject><subject>PATIENTS</subject><subject>PHOSPHORUS COMPOUNDS</subject><subject>PYROPHOSPHATES</subject><subject>RADIOISOTOPE SCANNING</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide Imaging</subject><subject>SCINTISCANNING</subject><subject>Technetium</subject><subject>TECHNETIUM 99</subject><subject>TECHNETIUM ISOTOPES</subject><subject>YEARS LIVING RADIOISOTOPES</subject><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEtLxDAURoP4GkfXblwUF-7ayaNNm6UMjg4MCKLrkKapjbRJTVJk_r0ZOgiuLhfOfXwHgFsEM4QoWkGUrbdvWUEznKEKnYAFKnCe5gVhp2ABIWRpSTC-BFfef8WWkrK4AOdViQmsFqDb2L63P-k0JkHJzqigpyFlbEh8EMbYySfj3tmxs37sRFDJsLdSuEaLPvFSm6A_nRh8ItqgXCLk9B_RphVOBm3NNThrRe_VzbEuwcfm6X39ku5en7frx10qCWMhlXVN66KtkVAVrChErJRMUiaVKItcYUpbwQglKoeNzBsMKWoYyhvYwLrGqCZLcD_vtT5oHl88xJLWGCUDjyYIozBCDzM0Ovs9KR_4oL1UfS-MipF5RRiJ56sIrmZQOuu9Uy0fnR6E23ME-cE_h4hH_7ygHPPoP07cHVdP9aCaP34WTn4Bw9iCuA</recordid><startdate>197708</startdate><enddate>197708</enddate><creator>Olson, H G</creator><creator>Lyons, K P</creator><creator>Aronow, W S</creator><creator>Brown, W T</creator><creator>Greenfield, R S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>197708</creationdate><title>Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction</title><author>Olson, H G ; Lyons, K P ; Aronow, W S ; Brown, W T ; Greenfield, R S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-cbb6b5fb1ae80860197c9c69cea754e266fa9363e40dc4d2061d914d0d0bb21b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>Acute Disease</topic><topic>Adult</topic><topic>Aged</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BETA-MINUS DECAY RADIOISOTOPES</topic><topic>BODY</topic><topic>CARDIOVASCULAR DISEASES</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>COUNTING TECHNIQUES</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DISEASES</topic><topic>Female</topic><topic>HEART</topic><topic>HOURS LIVING RADIOISOTOPES</topic><topic>Humans</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>ISOMERIC NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>Male</topic><topic>Middle Aged</topic><topic>MUSCLES</topic><topic>MYOCARDIAL INFARCTION</topic><topic>Myocardial Infarction - diagnosis</topic><topic>MYOCARDIUM</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANS</topic><topic>OXYGEN COMPOUNDS</topic><topic>PATIENTS</topic><topic>PHOSPHORUS COMPOUNDS</topic><topic>PYROPHOSPHATES</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>SCINTISCANNING</topic><topic>Technetium</topic><topic>TECHNETIUM 99</topic><topic>TECHNETIUM ISOTOPES</topic><topic>YEARS LIVING RADIOISOTOPES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Olson, H G</creatorcontrib><creatorcontrib>Lyons, K P</creatorcontrib><creatorcontrib>Aronow, W S</creatorcontrib><creatorcontrib>Brown, W T</creatorcontrib><creatorcontrib>Greenfield, R S</creatorcontrib><creatorcontrib>Univ. of California, Irvine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Olson, H G</au><au>Lyons, K P</au><au>Aronow, W S</au><au>Brown, W T</au><au>Greenfield, R S</au><aucorp>Univ. of California, Irvine</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><addtitle>Circulation</addtitle><date>1977-08</date><risdate>1977</risdate><volume>56</volume><issue>2</issue><spage>181</spage><epage>187</epage><pages>181-187</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><abstract>Technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigrams were obtained in 68 patients during acute myocardial infarction (AMI) and at follow-up 15.9 +/- 8.8 weeks later. All patients with AMI had a positive scintigram (2+ or greater); only one of 46 control patients (2%) had a positive (2+) scintigram. At follow-up scintigraphy 6 to 37 weeks following AMI, 57% of patients had a persistently positive scintigram even though recurrent AMI was suspected in only one of these patients. Patients with persistently positive scintigrams tended to have more severe disease as evidenced by compensated congested heart failure (41%) persistent angina (77%), and ECG evidence of ventricular dyssynergy (51%), We conclude that 1) in patients with prior AMI, a 2+ abnormality on 99mTc-PYP scintigram may not represent new AMI; 2) a persistently positive 99mTc- PYP scintigram may have prognostic implications since it occurs predominantly in patients with severe symptomatic coronary disease.</abstract><cop>United States</cop><pmid>872308</pmid><doi>10.1161/01.CIR.56.2.181</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Circulation (New York, N.Y.), 1977-08, Vol.56 (2), p.181-187 |
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| source | Journals@Ovid Complete - AutoHoldings; MEDLINE; American Heart Association Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics Acute Disease Adult Aged BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES BODY CARDIOVASCULAR DISEASES CARDIOVASCULAR SYSTEM COUNTING TECHNIQUES DIAGNOSIS DIAGNOSTIC TECHNIQUES DISEASES Female HEART HOURS LIVING RADIOISOTOPES Humans INTERMEDIATE MASS NUCLEI ISOMERIC NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES Male Middle Aged MUSCLES MYOCARDIAL INFARCTION Myocardial Infarction - diagnosis MYOCARDIUM NUCLEI ODD-EVEN NUCLEI ORGANS OXYGEN COMPOUNDS PATIENTS PHOSPHORUS COMPOUNDS PYROPHOSPHATES RADIOISOTOPE SCANNING RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging SCINTISCANNING Technetium TECHNETIUM 99 TECHNETIUM ISOTOPES YEARS LIVING RADIOISOTOPES |
| title | Follow-up technetium-99m stannous pyrophosphate myocardial scintigrams after acute myocardial infarction |
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