Effects of Vitamin B6 Deficiency on Thymic Epithelial Cells and T Lymphocyte Differentiation

Dietary vitamin B6 (pyridoxine) deficiency in young Lewis rats results in a reduction of T lymphocyte numbers and defects of cellular immunocompetence. In vitro studies of thymic epithelial (TE) cells, responsible for inducing T lymphocyte differentiation, revealed that maintenance on a vitamin B6 d...

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Veröffentlicht in:	The Journal of immunology (1950) 1978-04, Vol.120 (4), p.1153-1159
Hauptverfasser:	Willis-Carr, J. I, St. Pierre, R. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells Cell Differentiation Concanavalin A - pharmacology Epithelium Lectins - pharmacology Lymphocyte Culture Test, Mixed Male Rats Rats, Inbred Lew T-Lymphocytes - cytology Thymectomy Thymus Gland - cytology Thymus Gland - pathology Vitamin B 6 Deficiency - immunology
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