Role of Sialic Acid in Survival of Erythrocytes in the Circulation: Interaction of Neuraminidase-Treated and Untreated Erythrocytes with Spleen and Liver at the Cellular Level

Sialidase (neuraminidase; acylneuraminyl hydrolase; EC 3.2.1.18)-treated erythrocytes obtained from different species are susceptible to rapid elimination from the circulation and are sequestered in the liver and spleen. The present studies were concerned with the mechanism of this clearance and how...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1977-04, Vol.74 (4), p.1521-1524
Hauptverfasser:	Aminoff, David, William F. Vorder Bruegge, Bell, William C., Sarpolis, Keith, Williams, Revius
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Blood Chemical suspensions Erythrocyte Aging Erythrocytes Erythrocytes - drug effects Erythrocytes - physiology Hepatocytes Kupffer cells Kupffer Cells - physiology Liver Liver - physiology Liver cells Male Neuraminidase - pharmacology Rats Sialic Acids - blood Spleen Spleen - physiology Spleen cells
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