Sickle cell hepatopathy

Hepatic dysfunction is a common finding in patients with sickle cell disease but viral hepatitis appears to be an unusual complication in the adult SS patient. Only five cases of viral hepatitis were recorded in 378 admissions for SS crisis. In contrast, hepatic crisis occurred as a distinct event i...

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Veröffentlicht in:	Southern medical journal (Birmingham, Ala.) Ala.), 1977-05, Vol.70 (5), p.533-537
1. Verfasser:	Sheehy, T W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anemia, Sickle Cell - complications Anemia, Sickle Cell - pathology Biopsy, Needle Cholecystitis - etiology Cholelithiasis - etiology Cholestasis - etiology Female Gallbladder - pathology Gallstones - etiology Hepatitis, Viral, Human - etiology Humans Liver Cirrhosis - etiology Liver Cirrhosis - pathology Liver Diseases - etiology Liver Diseases - pathology Male Retrospective Studies
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creator	Sheehy, T W
description	Hepatic dysfunction is a common finding in patients with sickle cell disease but viral hepatitis appears to be an unusual complication in the adult SS patient. Only five cases of viral hepatitis were recorded in 378 admissions for SS crisis. In contrast, hepatic crisis occurred as a distinct event in 9% of 88 patients with sickle cell anemia. This entity must be differentiated from acute cholecystitis or viral hepatitis. Transiently abnormal results of hepatitic function tests were observed in another 26 patients with extrahepatic crisis. Cirrhosis is relatively common and often the terminal event in SS disease. Choledocholithiasis and cholecystitis are infrequent complications despite the prevalence of gallstones in SS anemia.
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Only five cases of viral hepatitis were recorded in 378 admissions for SS crisis. In contrast, hepatic crisis occurred as a distinct event in 9% of 88 patients with sickle cell anemia. This entity must be differentiated from acute cholecystitis or viral hepatitis. Transiently abnormal results of hepatitic function tests were observed in another 26 patients with extrahepatic crisis. Cirrhosis is relatively common and often the terminal event in SS disease. Choledocholithiasis and cholecystitis are infrequent complications despite the prevalence of gallstones in SS anemia.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anemia, Sickle Cell - complications</subject><subject>Anemia, Sickle Cell - pathology</subject><subject>Biopsy, Needle</subject><subject>Cholecystitis - etiology</subject><subject>Cholelithiasis - etiology</subject><subject>Cholestasis - etiology</subject><subject>Female</subject><subject>Gallbladder - pathology</subject><subject>Gallstones - etiology</subject><subject>Hepatitis, Viral, Human - etiology</subject><subject>Humans</subject><subject>Liver Cirrhosis - etiology</subject><subject>Liver Cirrhosis - pathology</subject><subject>Liver Diseases - etiology</subject><subject>Liver Diseases - pathology</subject><subject>Male</subject><subject>Retrospective Studies</subject><issn>0038-4348</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kLtPxDAMxjPwOg5mFoab2ApO83JGdOIlncQAzFGSJrpCS0vTDvff09LjLFmWre-zrR8hKwq3FLS6gzGUpDSjWikQY5dNIzwiCwCGGWccz8h5Sp-TUKA8JSeoRqdakKu30n9VYeVDVa22obV9M-Z2d0GOo61SuNzXJfl4fHhfP2eb16eX9f0m8wx0n3EH6FzBnSxszjRjPMcIngqWOxGEFJ5yHSVQKylAEYXkiFoqFFEG6YAtyc28t-2anyGk3tRlmp6x36EZkkGmASSbhDgLfdek1IVo2q6sbbczFMyEwfxjMAcMfyMcrdf7G4OrQ3EwzgzYL3GQVxE</recordid><startdate>197705</startdate><enddate>197705</enddate><creator>Sheehy, T W</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197705</creationdate><title>Sickle cell hepatopathy</title><author>Sheehy, T W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c309t-4b08bbd4b6da23933428f0c1532b5e565c149f601a6100df5648896785f6e6b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anemia, Sickle Cell - complications</topic><topic>Anemia, Sickle Cell - pathology</topic><topic>Biopsy, Needle</topic><topic>Cholecystitis - etiology</topic><topic>Cholelithiasis - etiology</topic><topic>Cholestasis - etiology</topic><topic>Female</topic><topic>Gallbladder - pathology</topic><topic>Gallstones - etiology</topic><topic>Hepatitis, Viral, Human - etiology</topic><topic>Humans</topic><topic>Liver Cirrhosis - etiology</topic><topic>Liver Cirrhosis - pathology</topic><topic>Liver Diseases - etiology</topic><topic>Liver Diseases - pathology</topic><topic>Male</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sheehy, T W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sheehy, T W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sickle cell hepatopathy</atitle><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle><addtitle>South Med J</addtitle><date>1977-05</date><risdate>1977</risdate><volume>70</volume><issue>5</issue><spage>533</spage><epage>537</epage><pages>533-537</pages><issn>0038-4348</issn><abstract>Hepatic dysfunction is a common finding in patients with sickle cell disease but viral hepatitis appears to be an unusual complication in the adult SS patient. 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identifier	ISSN: 0038-4348
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subjects	Adolescent Adult Anemia, Sickle Cell - complications Anemia, Sickle Cell - pathology Biopsy, Needle Cholecystitis - etiology Cholelithiasis - etiology Cholestasis - etiology Female Gallbladder - pathology Gallstones - etiology Hepatitis, Viral, Human - etiology Humans Liver Cirrhosis - etiology Liver Cirrhosis - pathology Liver Diseases - etiology Liver Diseases - pathology Male Retrospective Studies
title	Sickle cell hepatopathy
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