Pharmacological studies of loperamide, an anti-diarrheal agent. II. Effects on peristalsis of the small intestine and colon in guinea pigs

Effects of loperamide on peristalsis in the guinea pig intestines were investigated in comparison with those of morphine and atropine. The following results were obtained. The ejection of intraluminal fluid produced by the peristaltic contraction of the isolated ileum was suppressed by loperamide at...

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Veröffentlicht in:	Folia Pharmacologica Japonica 1978, Vol.74(1), pp.155-163
Hauptverfasser:	SOHJI, Yukinobu, KAWASHIMA, Katsuyoshi, SHIMIZU, Masanao
Format:	Artikel
Sprache:	jpn
Schlagworte:	Animals Atropine - pharmacology Colon - drug effects Depression, Chemical Dose-Response Relationship, Drug Gastrointestinal Motility - drug effects Guinea Pigs Ileum - drug effects In Vitro Techniques Intestine, Small - drug effects Loperamide - administration & dosage Loperamide - pharmacology Male Morphine - pharmacology Peristalsis - drug effects Piperidines - pharmacology Time Factors
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