SOLID PHASE SYNTHESIS AND SOME HORMONAL ACTIVITIES OF 8-L-HOMOARGININE-VASOTOCIN AND 1-DEAMINO-8-L-HOMOARGININE-VASOTOCIN

8‐L‐Homoarginine‐vasotocin and its I‐deamino derivative were synthesized by the solid phase method. Both compounds possessed high activities in the uterus contraction and fowl depressor assays and showed higher pressor activities than the corresponding vasopressins. Homoarginine‐vasotocin, unexpecte...

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Veröffentlicht in:	International Journal of Peptide and Protein Research 1977-03, Vol.9 (3), p.182-186
Hauptverfasser:	Larsson, Lars-Eric, Lindeberg, E. Gunnar G., Melin, Per
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological Assay Diuresis - drug effects Female Pressure Rats Structure-Activity Relationship Uterine Contraction - drug effects Vasotocin - analogs & derivatives Vasotocin - chemical synthesis Vasotocin - pharmacology
Online-Zugang:	Volltext
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