A computational model of pulmonary gas transport incorporating effective diffusion
A computational model of gas transport in the lung is described which remedies many of the deficiencies of previous models, as listed by Chang and Farhi (1973), in that it allows for fluctuating lung dimensions, gas exchange, simultaneous convection and diffusion, and the enhanced effective diffusio...
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Veröffentlicht in: | Respiration physiology 1977-01, Vol.29 (1), p.101-123 |
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creator | Pack, A. Hooper, M.B. Nixon, W. Taylor, J.C. |
description | A computational model of gas transport in the lung is described which remedies many of the deficiencies of previous models, as listed by Chang and Farhi (1973), in that it allows for fluctuating lung dimensions, gas exchange, simultaneous convection and diffusion, and the enhanced effective diffusion that occurs when convective flow is also present. The results of calculations using the model are presented, showing the maximum effect of Taylor diffusion. The actual magnitude of Taylor diffusion, suitably modified to allow for the disturbed conditions within the lung, is considered in the light of recent experiments. |
doi_str_mv | 10.1016/0034-5687(77)90121-9 |
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The results of calculations using the model are presented, showing the maximum effect of Taylor diffusion. The actual magnitude of Taylor diffusion, suitably modified to allow for the disturbed conditions within the lung, is considered in the light of recent experiments.</description><identifier>ISSN: 0034-5687</identifier><identifier>DOI: 10.1016/0034-5687(77)90121-9</identifier><identifier>PMID: 847307</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Carbon Dioxide ; Convection in the lung ; Diffusion in the lung ; Lung - physiology ; Models, Biological ; Nitrogen ; Oxygen ; Pressure ; Pulmonary Diffusing Capacity ; Pulmonary gas exchange ; Respiration ; Space life sciences ; Taylor diffusion</subject><ispartof>Respiration physiology, 1977-01, Vol.29 (1), p.101-123</ispartof><rights>1977</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-900c6349589ae8f2a6bebd3ec9117a72ab1f7a19ccbcd4551fe900c2f2c32ca93</citedby><cites>FETCH-LOGICAL-c451t-900c6349589ae8f2a6bebd3ec9117a72ab1f7a19ccbcd4551fe900c2f2c32ca93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/847307$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pack, A.</creatorcontrib><creatorcontrib>Hooper, M.B.</creatorcontrib><creatorcontrib>Nixon, W.</creatorcontrib><creatorcontrib>Taylor, J.C.</creatorcontrib><title>A computational model of pulmonary gas transport incorporating effective diffusion</title><title>Respiration physiology</title><addtitle>Respir Physiol</addtitle><description>A computational model of gas transport in the lung is described which remedies many of the deficiencies of previous models, as listed by Chang and Farhi (1973), in that it allows for fluctuating lung dimensions, gas exchange, simultaneous convection and diffusion, and the enhanced effective diffusion that occurs when convective flow is also present. The results of calculations using the model are presented, showing the maximum effect of Taylor diffusion. The actual magnitude of Taylor diffusion, suitably modified to allow for the disturbed conditions within the lung, is considered in the light of recent experiments.</description><subject>Carbon Dioxide</subject><subject>Convection in the lung</subject><subject>Diffusion in the lung</subject><subject>Lung - physiology</subject><subject>Models, Biological</subject><subject>Nitrogen</subject><subject>Oxygen</subject><subject>Pressure</subject><subject>Pulmonary Diffusing Capacity</subject><subject>Pulmonary gas exchange</subject><subject>Respiration</subject><subject>Space life sciences</subject><subject>Taylor diffusion</subject><issn>0034-5687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhnPwa139B3vISfRQTfqV5iLI4hcsCKLnkKaTJdI2NUkX_Pemdtmjp5l5Z94X5kFoRcktJbS8IyTLk6Ks2DVjN5zQlCb8CC0O8hk69_6LxLkk5Sk6qXKWEbZA7w9Y2W4YgwzG9rLFnW2gxVbjYWy7qLgfvJUeByd7P1gXsOmVdbGLhn6LQWtQwewAN0br0ceQC3SsZevhcl-X6PPp8WP9kmzenl_XD5tE5QUNCSdElVnOi4pLqHQqyxrqJgPFKWWSpbKmmknKlapVkxcF1TBZUp2qLFWSZ0t0NecOzn6P4IPojFfQtrIHO3pRZVWZ5mw6zOdD5az3DrQYnOniZ4ISMdETEyYxYRKMiT96YrKt9vlj3UFzMM3o4vp-XkP8cWfACa8M9Aoa4yIS0Vjzf_4vO7eCcQ</recordid><startdate>19770101</startdate><enddate>19770101</enddate><creator>Pack, A.</creator><creator>Hooper, M.B.</creator><creator>Nixon, W.</creator><creator>Taylor, J.C.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19770101</creationdate><title>A computational model of pulmonary gas transport incorporating effective diffusion</title><author>Pack, A. ; Hooper, M.B. ; Nixon, W. ; Taylor, J.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-900c6349589ae8f2a6bebd3ec9117a72ab1f7a19ccbcd4551fe900c2f2c32ca93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Carbon Dioxide</topic><topic>Convection in the lung</topic><topic>Diffusion in the lung</topic><topic>Lung - physiology</topic><topic>Models, Biological</topic><topic>Nitrogen</topic><topic>Oxygen</topic><topic>Pressure</topic><topic>Pulmonary Diffusing Capacity</topic><topic>Pulmonary gas exchange</topic><topic>Respiration</topic><topic>Space life sciences</topic><topic>Taylor diffusion</topic><toplevel>online_resources</toplevel><creatorcontrib>Pack, A.</creatorcontrib><creatorcontrib>Hooper, M.B.</creatorcontrib><creatorcontrib>Nixon, W.</creatorcontrib><creatorcontrib>Taylor, J.C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Respiration physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pack, A.</au><au>Hooper, M.B.</au><au>Nixon, W.</au><au>Taylor, J.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A computational model of pulmonary gas transport incorporating effective diffusion</atitle><jtitle>Respiration physiology</jtitle><addtitle>Respir Physiol</addtitle><date>1977-01-01</date><risdate>1977</risdate><volume>29</volume><issue>1</issue><spage>101</spage><epage>123</epage><pages>101-123</pages><issn>0034-5687</issn><abstract>A computational model of gas transport in the lung is described which remedies many of the deficiencies of previous models, as listed by Chang and Farhi (1973), in that it allows for fluctuating lung dimensions, gas exchange, simultaneous convection and diffusion, and the enhanced effective diffusion that occurs when convective flow is also present. 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subjects | Carbon Dioxide Convection in the lung Diffusion in the lung Lung - physiology Models, Biological Nitrogen Oxygen Pressure Pulmonary Diffusing Capacity Pulmonary gas exchange Respiration Space life sciences Taylor diffusion |
title | A computational model of pulmonary gas transport incorporating effective diffusion |
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