An autoradiographic evaluation of the regeneration of corneal epithelium in Bufo marinus

An autoradiographic evaluation of the regeneration of corneal epithelium in Bufo marinus

Epithelial regeneration following scraping of a central portion of corneal epithelium of the toad, Bufo marinus, was studied. Wound closure occurred by migration of a single layer of epithelial cells from adjacent noninjured areas. Autoradiography indicated that following wound closure at two days a...

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Veröffentlicht in:The Journal of experimental zoology 1978-02, Vol.203 (2), p.201-206
Hauptverfasser: Grillo, R. S., Knowles, B. A., Cooperstein, D. F.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Bufo marinus
Cornea - cytology
Cornea - physiology
Epithelial Cells
Female
Male
Regeneration
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container_title The Journal of experimental zoology
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creator Grillo, R. S.
Knowles, B. A.
Cooperstein, D. F.
description Epithelial regeneration following scraping of a central portion of corneal epithelium of the toad, Bufo marinus, was studied. Wound closure occurred by migration of a single layer of epithelial cells from adjacent noninjured areas. Autoradiography indicated that following wound closure at two days after scraping, DNA synthesis began in these epithelial cells covering the former scraped area, and was even more pronounced three days after scraping. At four days the former denuded area was covered by an epithelium two to four cells thick and by the fifth day regeneration was complete. These studies also indicated that mitotic time in this organism is rapid.
doi_str_mv 10.1002/jez.1402030203
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These studies also indicated that mitotic time in this organism is rapid.</description><subject>Animals</subject><subject>Bufo marinus</subject><subject>Cornea - cytology</subject><subject>Cornea - physiology</subject><subject>Epithelial Cells</subject><subject>Female</subject><subject>Male</subject><subject>Regeneration</subject><issn>0022-104X</issn><issn>1097-010X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAQxy3EqxRWJgZPbCnnOC-PUJVCVcEComKxHPcChjQudgKUT09QqiImhtNJ93_o9CPkmMGAAYRnL_g1YBGEwH9mi_QYiDQABrNt0msNYcAgmu2TA-9fABiLId0juxGLGeM9MjuvqGpq69Tc2Cenls9GU3xXZaNqYytqC1o_I3X4hBW6zU1bV6EqKS5NK5emWVBT0YumsHShnKkaf0h2ClV6PFrvPrm_HN0Nr4Lp7fh6eD4NNE9THrAiEWkYRTxLEATPtAAFLNW5VkmiAbXK25sWgheYJ2GRJPMoU4qJPM4KzjTvk9Oud-nsW4O-lgvjNZalqtA2XmY8i2OIRWscdEbtrPcOC7l0pn12JRnIH5KyJSl_SbaBk3Vzky9wvrF36FpZdPKHKXH1T5mcjB7_VAdd1vgaPzdZ5V5lkvI0lg83Ywl3WTS5yB7lmH8Ds-mPQw</recordid><startdate>197802</startdate><enddate>197802</enddate><creator>Grillo, R. 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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Animals
Bufo marinus
Cornea - cytology
Cornea - physiology
Epithelial Cells
Female
Male
Regeneration
title An autoradiographic evaluation of the regeneration of corneal epithelium in Bufo marinus
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