Prostacyclin: A Potentially Valuable Agent for Preserving Myocardial Tissue in Acute Myocardial Ischemia

Prostacyclin, a potent, naturally occurring prostaglandin exerts a variety of cardiovascular and cellular actions of potential value in acute myocardial ischemia. These properties include the reduction of systemic blood pressure without changing heart rate, the lowering of coronary vascular and tota...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1978-04, Vol.200 (4337), p.52-54
Hauptverfasser:	Lefer, Allan M., Ogletree, Martin L., Smith, J. Bryan, Silver, Melvin J., Nicolaou, Kyriacos C., Barnette, William E., Gasic, Gregory P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood pressure Blood Pressure - drug effects Cats Coronary Circulation - drug effects Coronary Disease - drug therapy Epoprostenol - pharmacology Epoprostenol - therapeutic use Heart rate Heart Rate - drug effects Hemodynamics - drug effects In Vitro Techniques Lysosomes - drug effects Lysosomes - enzymology Myocardial Contraction - drug effects Myocardial ischemia Perfusion Platelet aggregation Platelet Aggregation - drug effects Prostaglandins Prostaglandins - pharmacology Thromboxanes Thromboxanes - blood Vascular resistance Vascular Resistance - drug effects Vasodilation Vehicles
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